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The Resource Transplantation immunology : methods and protocols, edited by Philip Hornick, Marlene Rose

Transplantation immunology : methods and protocols, edited by Philip Hornick, Marlene Rose

Contributor
Summary
Technical innovations in the laboratory over the past ten years have greatly improved our understanding of the immunological mechanisms of transplanted organ rejection. In Transplantation Immunology: Methods and Protocols, leading experts in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods of utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The areas of tolerance induction and reprogramming of the immune system are also covered, along with a discussion of up-to-date methods of organ preservation, of today's optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection. State of the art and highly practical, Transplantation Immunology: Methods and Protocols illuminates for clinicians and scientists-both newcomers and experts-the new world of detecting and monitoring patients' immunological responses to solid organ transplantation
Language
eng
Work
Publication
Extent
1 online resource (x, 429 pages)
Contents
  • Current status of renal transplantation / Christopher J. Callaghan and Andrew J. Bradley -- Current status of liver transplantation / Peter J. Friend and Charles J. Imber -- Current status of clinical islet cell transplantation / Jonathan R.T. Lakey, Mohammadreza Mirbolooki, and A.M. James Shapiro -- Current status of lung transplantation / Allan R. Glanville -- Chronic rejection in the heart / Philip Hornick and Marlene Rose -- Direct and indirect allorecognition / Philip Hornick -- HLA typing and its influence on organ transplantation / Stephene Sheldon and Kay Poulton -- Strategies for gene transfer to solid organs : viral vectors / Charlotte Lawson -- Nonviral vectors / Louise Collins -- Detection and clinical relevance of antibodies after transplantation / John D. Smith and Marlene Rose
  • Reprogramming the immune system using antibodies / Luis Graca and Hermann Waldmann -- In vitro assays for immune monitoring in transplantation / Maria P. Hernandez-Fuentes and Alan Salama -- Proteomics and laser microdissection / Emma McGregor and Ayesha De Souza -- Real-time quantitative polymerase chain reaction in cardiac transplant research / Leanne E. Felkin, Ann B. Taegtmeyer, and Paul J.R. Barton -- Organ preservation / Mark Hicks [and others] -- Pharmacological manipulation of the rejection response / Peter Mark Anthony Hopkins -- Experimental models of graft arteriosclerosis / Bezhad Soleimani and Victor C. Shi
Isbn
9781597451222
Link
http://libproxy.rpi.edu/login?url=http://link.springer.com/10.1385/1597450499
Instance
Label
Transplantation immunology : methods and protocols
Title
Transplantation immunology
Title remainder
methods and protocols
Statement of responsibility
edited by Philip Hornick, Marlene Rose
Contributor
Subject
Language
eng
Summary
Technical innovations in the laboratory over the past ten years have greatly improved our understanding of the immunological mechanisms of transplanted organ rejection. In Transplantation Immunology: Methods and Protocols, leading experts in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods of utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The areas of tolerance induction and reprogramming of the immune system are also covered, along with a discussion of up-to-date methods of organ preservation, of today's optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection. State of the art and highly practical, Transplantation Immunology: Methods and Protocols illuminates for clinicians and scientists-both newcomers and experts-the new world of detecting and monitoring patients' immunological responses to solid organ transplantation
Member of
Cataloging source
COO
Illustrations
illustrations
Index
index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Series statement
Methods in molecular biology,
Series volume
333
Transplantation immunology : methods and protocols, edited by Philip Hornick, Marlene Rose
Label
Transplantation immunology : methods and protocols, edited by Philip Hornick, Marlene Rose
Link
http://libproxy.rpi.edu/login?url=http://link.springer.com/10.1385/1597450499
Publication
Related Contributor
Related Location
Related Agents
Related Authorities
Related Subjects
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Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
  • Current status of renal transplantation / Christopher J. Callaghan and Andrew J. Bradley -- Current status of liver transplantation / Peter J. Friend and Charles J. Imber -- Current status of clinical islet cell transplantation / Jonathan R.T. Lakey, Mohammadreza Mirbolooki, and A.M. James Shapiro -- Current status of lung transplantation / Allan R. Glanville -- Chronic rejection in the heart / Philip Hornick and Marlene Rose -- Direct and indirect allorecognition / Philip Hornick -- HLA typing and its influence on organ transplantation / Stephene Sheldon and Kay Poulton -- Strategies for gene transfer to solid organs : viral vectors / Charlotte Lawson -- Nonviral vectors / Louise Collins -- Detection and clinical relevance of antibodies after transplantation / John D. Smith and Marlene Rose
  • Reprogramming the immune system using antibodies / Luis Graca and Hermann Waldmann -- In vitro assays for immune monitoring in transplantation / Maria P. Hernandez-Fuentes and Alan Salama -- Proteomics and laser microdissection / Emma McGregor and Ayesha De Souza -- Real-time quantitative polymerase chain reaction in cardiac transplant research / Leanne E. Felkin, Ann B. Taegtmeyer, and Paul J.R. Barton -- Organ preservation / Mark Hicks [and others] -- Pharmacological manipulation of the rejection response / Peter Mark Anthony Hopkins -- Experimental models of graft arteriosclerosis / Bezhad Soleimani and Victor C. Shi
http://library.link/vocab/cover_art
https://contentcafe2.btol.com/ContentCafe/Jacket.aspx?Return=1&Type=S&Value=9781597451222&userID=ebsco-test&password=ebsco-test
Dimensions
unknown
http://library.link/vocab/discovery_link
{'f': 'http://opac.lib.rpi.edu/record=b3357038'}
Extent
1 online resource (x, 429 pages)
Form of item
online
Isbn
9781597451222
Lccn
2005028830
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations.
Specific material designation
remote

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