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The Resource Toll-like receptors : practice and methods, edited by Claire E. McCoy

Toll-like receptors : practice and methods, edited by Claire E. McCoy

Toll-like receptors : practice and methods
Toll-like receptors
Title remainder
practice and methods
Statement of responsibility
edited by Claire E. McCoy
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index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Series statement
  • Methods in molecular biology,
  • Springer protocols
Series volume
Summary expansion
This second edition volume expands on the first edition with new developments on Toll-Like Receptors (TLRs) controlling events such as cross-priming of associated pattern recognition receptors, post-transcriptional regulation, interaction with other cellular and biologic systems, and cancer progression. This book is divided into five sections: Part I outlines methods for TLR detection, interaction, and intracellular trafficking; Part II describes methods and assays to investigate how TLRs cross-prime other pattern recognition receptors, including intracellular DNA receptors and inflammasome formation; Part III highlights RNA regulation, detailing how TLRs can induce RNA transcripts and molecules such as lncRNAs and microRNAs; Part IV explores TLR detection and activation in systems such as epithelial barrier function, metabolism and the circadian clock, as well as cellular systems including T and B lymphocytes; and Part V describes models to delineate the role of TLRs in diseases such as dermatitis, arthritis, and gastric cancer. Written in the highly successful "Methods in Molecular Biology "series format, each chapter contains a summary, a list of required materials, step-by-step, readily reproducible laboratory protocols, useful notes to investigate TLRs in cell culture, systems and disease, and tips on troubleshooting and avoiding known pitfalls. Practical and cutting-edge, "Toll-Like Receptors: Methods and Protocols, Second Edition" is a valuable resource to any immunologist, molecular or medical biologist working in a laboratory setting. It will add skill to both students and the more advanced molecular biologist who wishes to learn a new technique or move to a different area within their current repertoire of practical knowledge
Toll-like receptors : practice and methods, edited by Claire E. McCoy
Toll-like receptors : practice and methods, edited by Claire E. McCoy
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Bibliography note
Includes bibliographical references and index
Carrier category
online resource
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  • Assessing the inhibitory activity of oligonucleotides on TLR7 sensing
  • Jonathan Ferrand and Michael P. Gantier
  • Methods for delivering DNA to intracellular receptors
  • Katryn J. Stacey [and others]
  • Detection of interaction between toll-like receptors and other transmembrane proteins by co-immunoprecipitation assay
  • Yu-Ran Lee, Wondae Kang, and You-Me Kim
  • Flow cytometry-based bead-binding assay for measuring receptor ligand specificity
  • Joris K. Sprokholt, Nina Hertoghs, and Teunis B.H. Geijtenbeek
  • Measuring monomer-to-filament transition of MAVS as an in vitro activity assay for RIG-I-Like receptors
  • Bin Wu, Yu-San Huoh, and Sun Hur
  • Toll-like receptors : ligands, cell-based models, and readouts for receptor action
  • Co-transcriptomic analysis by RNA sequencing to simultaneously measure regulated gene expression in host and bacterial pathogen
  • Timothy Ravasi [and others]
  • Simple methods to investigate microRNA induction in response to toll-like receptors
  • Victoria G. Lyons and Claire E. McCoy
  • Determining the function of long noncoding RNA in innate immunity
  • Susan Carpenter
  • Analysis of post-transcriptional gene regulation of nod-like receptors via the 3'UTR
  • Moritz Haneklaus
  • TLR function in murine CD4+ T lymphocytes and their role in inflammation
  • Stephanie Flaherty and Joseph M. Reynolds
  • Jennifer K. Dowling and Jérome Dellacasagrande
  • Analysis by flow cytometry of B-cell activation and antibody responses induced by toll-like receptors
  • Egest J. Pone
  • Toll-like receptor-dependent immune complex activation of B cells and dendritic cells
  • Krishna L. Moody [and others]
  • Analysis of TLR-induced metabolic changes in dendritic cells using the seahorse XFe96 extracellular flux analyzer
  • Leonard R. Pelgrom, Alwin J. van der Ham, and Bart Everts
  • Toll-like receptor signalling and the control of intestinal barrier function
  • Daniel G.W. Johnston and Sinéad C. Corr
  • Understanding the role of cellular molecular clocks in controlling the innate immune response
  • Anne M. Curtis and Caio T. Fagundes
  • Bioinformatic analysis of toll-like receptor sequences and structures
  • Methods to investigate the role of toll-like receptors in allergic contact dermatitis
  • Marc Schmidt, Matthias Goebeler, and Stefan F. Martin
  • Allergens and activation of the toll-like receptor response
  • Tom P. Monie and Clare E. Bryant
  • Investigating the role of toll-like receptors in models of arthritis
  • Anna M. Piccinini [and others]
  • Delineating the role of toll-like receptors in the neuro- inflammation model EAE
  • Francesca Fallarino [and others]
  • Use of miRNA antagonists in the alleviation of inflammatory disorders
  • Lucien P. Garo and Gopal Murugaiyan
  • Tom P. Monie, Nicholas J. Gay, and Monique Gangloff
  • Investigating the role of toll-like receptors in mouse models of gastric cancer
  • Alison C. West and Brendan J. Jenkins
  • Toll-like receptor interactions measured by microscopic and flow cytometric FRET
  • Gabor L. Horvath, Pia Langhoff, and Eicke Latz
  • Using confocal microscopy to investigate intracellular trafficking of toll-like receptors
  • Harald Husebye and Sarah L. Doyle
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2nd ed.
1 online resource (xiv, 455 pages)
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illustrations (some color).
unknown sound
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Library Locations

    • Folsom LibraryBorrow it
      110 8th St, Troy, NY, 12180, US
      42.729766 -73.682577
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