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The Resource Toll-like receptors : methods and protocols, edited by Claire E. McCoy, Luke A.J. O'Neill

Toll-like receptors : methods and protocols, edited by Claire E. McCoy, Luke A.J. O'Neill

Label
Toll-like receptors : methods and protocols
Title
Toll-like receptors
Title remainder
methods and protocols
Statement of responsibility
edited by Claire E. McCoy, Luke A.J. O'Neill
Contributor
Subject
Language
eng
Summary
In addition to their invaluable role in the fight against infection, Toll-Like Receptors (TLRs) in an under- or over-active state can lead to the pathogenesis of disease, making these receptors a key focal point for many research laboratories. In Toll-Like Receptors: Methods and Protocols, experts in the field contribute techniques currently used to study TLRs, their downstream signalling pathways, and their role in the pathogenesis of disease, with sections examining TLR expression and the application of genetic techniques and microarray analysis to TLR research. Written in the highly successful Methods in Molecular Biology series format, chapters include brief introductions to the topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and Notes sections highlighting tips on troubleshooting and avoiding known pitfalls. Versatile and cutting-edge, Toll-Like Receptors: Methods and Protocols provides an ideal manual for a wide range of biologists and medical researchers studying these vital components of the immune system
Member of
Cataloging source
CUS
Illustrations
illustrations
Index
index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Series statement
  • Methods in molecular biology,
  • Springer protocols
Series volume
517
Toll-like receptors : methods and protocols, edited by Claire E. McCoy, Luke A.J. O'Neill
Label
Toll-like receptors : methods and protocols, edited by Claire E. McCoy, Luke A.J. O'Neill
Link
http://libproxy.rpi.edu/login?url=http://link.springer.com/10.1007/978-1-59745-541-1
Publication
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Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
mixed
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Expression analysis of the toll-like receptors in human peripheral blood mononuclear cells / Jakub Siednienko and Sinead M. Miggin -- Ligands, cell-based models, and readouts required for toll-like receptor action / Jérôme Dellacasagrande -- Toll-like receptor interactions imaged by FRET microscopy and GFP fragment reconstitution / Gabor Horvath, Scott Young and Eicke Latz -- Predicting toll-like receptor structures and characterizing ligand binding / Joshua N. Leonard [and others] -- Bioinformatic analysis of toll-like receptor sequences and structures / Tom P. Monie, Nicholas J. Gay and Monique Gangloff -- Expression, purification, and crystallization of toll/interleukin-1 receptor (TIR) domains / Xiao Tao and Liang Tong -- Proteomic analysis of protein complexes in toll-like receptor biology / Kiva Brennan and Caroline A. Jefferie -- 2D-DIGE : comparative proteomics of cellular signalling pathways / Nadia Ben Larbi and Caroline Jefferies -- MAPPIT (Mammalian Protein-Protein Interaction Trap) analysis of early steps in toll-like receptor signalling / Peter Ulrichts [and others] -- Analysis of the functional role of toll-like receptor-4 tyrosine phosphorylation / Andrei E. Medvedev and Wenji Piao -- Analysis of ubiquitin degradation and phosphorylation of proteins / Pearl Gray -- The generation of highly purified primary human neutrophils and assessment of apoptosis in response to toll-like receptor ligands / Lisa C. Parker [and others] -- Cellular expression of A20 and ABIN-3 in response to toll-like receptor-4 stimulation / Kelly Verhelst [and others] -- Characterisation of viral proteins that Inhibit toll-like receptor signal transduction / Julianne Stack and Andrew G. Bowie -- Genetic dissection of toll-like receptor signaling using ENU mutagenesis / Kasper Hoebe -- Microarray experiments to uncover toll-like receptor function / Harry Björkbacka -- Uncovering novel gene function in toll-like receptor signalling using siRNA / Michael Carty [and others] -- Genotyping methods to analyse polymorphisms in toll-like receptors and disease / Chiea-Chuen Khor -- Experimental models of acute infection and toll-like receptor driven septic shock / Ruth Ferstl [and others] -- Toll-like receptors and rheumatoid arthritis / Fabia Brentano, Diego Kyburz and Steffen Gay -- Practical techniques for detection of toll-like receptor-4 in the human intestine / Ryan Ungaro [and others] -- Toll-like receptor-dependent immune complex activation of B cells and dendritic cells / Melissa B. Uccellini [and others] -- Innate immunity, toll-like receptors, and atherosclerosis : mouse models and methods / Rosalinda Sorrentino and Moshe Arditi -- Generation of parasite antigens for use in toll-like receptor research / Philip Smith, Niamh E. Mangan and Padraic G. Fallon -- Biomarkers measuring the activity of toll-like receptor ligands in clinical developmentrograms / Paul Sims, Robert L. Coffman, and Edith M. Hessel
http://library.link/vocab/cover_art
https://contentcafe2.btol.com/ContentCafe/Jacket.aspx?Return=1&Type=S&Value=9781597455411&userID=ebsco-test&password=ebsco-test
Dimensions
unknown
http://library.link/vocab/discovery_link
{'f': 'http://opac.lib.rpi.edu/record=b3357364'}
Extent
1 online resource (xiv, 447 pages)
Form of item
online
Isbn
9781597455411
Lccn
2008943238
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations.
Sound
unknown sound
Specific material designation
remote

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