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The Resource Telomerase inhibition : strategies and protocols, edited by Lucy G. Andrews and Trygve O. Tollefsbol

Telomerase inhibition : strategies and protocols, edited by Lucy G. Andrews and Trygve O. Tollefsbol

Label
Telomerase inhibition : strategies and protocols
Title
Telomerase inhibition
Title remainder
strategies and protocols
Statement of responsibility
edited by Lucy G. Andrews and Trygve O. Tollefsbol
Contributor
Subject
Genre
Language
eng
Summary
Due in part to the selective nature of telomerase inhibition as an anticancer approach, the field has expanded considerably in the past decade. The recent advances in methods of telomerase inhibition encompass many different areas of research including molecular biology, cell biology, biochemistry, oncology and gerontology. Telomerase Inhibition provides methods and protocols for those researchers. The techniques described in this book should provide the researcher with a diverse and comprehensive set of tools with which to study telomerase inhibition. Leaders in the field provide recently developed methods that have widespread application such as targeting the telomerase holoenzyme, its RNA template and other elements associated with telomerase activity. Additional methods involving the screening of telomerase inhibitors and telomerase inhibition combined with other chemotherapeutic agents are presented. This text, on the cutting edge of the field, will provide investigators with the most recent methods applied to the expanding field of telomerase inhibition
Member of
Cataloging source
VVL
Illustrations
illustrations
Index
index present
Language note
English
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Series statement
Methods in molecular biology
Series volume
v. 405
Telomerase inhibition : strategies and protocols, edited by Lucy G. Andrews and Trygve O. Tollefsbol
Label
Telomerase inhibition : strategies and protocols, edited by Lucy G. Andrews and Trygve O. Tollefsbol
Link
http://libproxy.rpi.edu/login?url=http://link.springer.com/10.1007/978-1-60327-070-0
Publication
Related Contributor
Related Location
Related Agents
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Related Subjects
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Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Methods of telomerase inhibition -- Telomerase inhibition by synthetic nucleic acids and chemosensitization in human bladder cancer cell lines -- hTERT knockdown in human embryonic kidney cells using double-stranded RNA -- RNA interference using a plasmid construct expressing a short-hairpin RNA -- Retrovirus-mediated RNA interference -- Telomerase inhibition and telomere targeting in hematopoietic cancer cell lines with small non-nucleosidic synthetic compounds (BIBR1532) -- Uses of telomerase peptides in anti-tumor immune therapy -- Establishing cell-based reporter systems for the analysis of hTERT expression -- Telomerase RNA inhibition using antisense oligonucleotide against human telomerase RNA linked to a 2',5'-oligoadenylate -- Knockdown of telomerase RNA using hammerhead ribozymes and RNA interference -- Evaluation of tankyrase inhibition in whole cells -- Inhibition of telomerase by targeting MAP kinase signaling -- Screening of telomerase inhibitors -- Telomerase inhibition combined with other chemotherapeutic reagents to enhance anti-cancer effect
http://library.link/vocab/cover_art
https://contentcafe2.btol.com/ContentCafe/Jacket.aspx?Return=1&Type=S&Value=9781597455015&userID=ebsco-test&password=ebsco-test
Dimensions
unknown
http://library.link/vocab/discovery_link
{'f': 'http://opac.lib.rpi.edu/record=b3357263'}
Extent
1 online resource (x, 193 pages)
Form of item
online
Isbn
9781597455015
Lccn
2007933147
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations.
Sound
unknown sound
Specific material designation
remote

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