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The Resource TCTP/tpt1 - Remodeling Signaling from Stem Cell to Disease, edited by Adam Telerman, Robert Amson, (electronic resource)

TCTP/tpt1 - Remodeling Signaling from Stem Cell to Disease, edited by Adam Telerman, Robert Amson, (electronic resource)

Label
TCTP/tpt1 - Remodeling Signaling from Stem Cell to Disease
Title
TCTP/tpt1 - Remodeling Signaling from Stem Cell to Disease
Statement of responsibility
edited by Adam Telerman, Robert Amson
Contributor
Editor
Subject
Language
eng
Summary
This book highlights the role of the Translationally Controlled Tumor Protein (TCTP) in cell signaling, cell fate and the resulting connection to disease development. It begins by discussing the structure/function of TCTP, before exploring its role in different species ranging from plants to Drosophila and covering fields such as development, the cytoskeleton, cell division, DNA fragility and apoptosis. In turn, the book{u2019}s final section is devoted to the role of TCTP in disease, namely asthma and diverse cancers, and ultimately as a target for the treatment of malignancies. What is the common denominator between all these processes and why is TCTP necessary in order for them to occur, even in the worst case such as cancer? The book seeks to provide meaningful answers to this and other key questions. Presenting a broad and revealing view on the topic, it offers an informative guide for scientists and students alike
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Is part of
Image bit depth
0
Literary form
non fiction
Series statement
Results and Problems in Cell Differentiation,
Series volume
64
TCTP/tpt1 - Remodeling Signaling from Stem Cell to Disease, edited by Adam Telerman, Robert Amson, (electronic resource)
Label
TCTP/tpt1 - Remodeling Signaling from Stem Cell to Disease, edited by Adam Telerman, Robert Amson, (electronic resource)
Link
http://libproxy.rpi.edu/login?url=http://dx.doi.org/10.1007/978-3-319-67591-6
Publication
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Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
1 Introduction: How we encountered TCTP and our purpose in studying it -- 2 Structural insights into TCTP and its interactions with ligands and proteins -- 3 Structure-Function relationship of TCTP -- 4 The Translational Controlled Tumour Protein TCTP: Biological Functions and Regulation -- 5 Current understanding of the TCTP interactome -- 6 Role and fate of TCTP in protein degradative pathways -- 7 Roles of the Translationally Controlled Tumor Protein (TCTP) in plant development -- 8 Function of Translationally controlled tumor protein in organ growth: Lessons from Drosophila studies -- 9 Translationally controlled tumor protein (TCTP/HRF) present in animal venoms -- 10 Tctp in Neuronal Circuitry Assembly -- 11 Elusive role of TCTP protein and mRNA in cell cycle and cytoskeleton regulation -- 12 TCTP protein and the cellular response to ionizing radiation-induced DNA damage -- 13 TCTP has a crucial role in the different stages of Prostate Cancer malignant progression -- 14 Role of TCTP for cellular differentiation and cancer therapy -- 15 Targeting TCTP with sertraline and thioridazine in cancer treatment -- 16 . History of Histamine Releasing Factor (HRF)/TCTP including a Potential Therapeutic Target in Asthma and Allergy
http://library.link/vocab/cover_art
https://contentcafe2.btol.com/ContentCafe/Jacket.aspx?Return=1&Type=S&Value=9783319675916&userID=ebsco-test&password=ebsco-test
Dimensions
unknown
http://library.link/vocab/discovery_link
{'f': 'http://opac.lib.rpi.edu/record=b4380140'}
Extent
X, 309 p. 51 illus., 36 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9783319675916
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote

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      42.729766 -73.682577
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