Coverart for item
The Resource Multi-drug resistance in cancer, edited by Jun Zhou

Multi-drug resistance in cancer, edited by Jun Zhou

Multi-drug resistance in cancer
Multi-drug resistance in cancer
Statement of responsibility
edited by Jun Zhou
With the devastating complication of cancer cells becoming simultaneously resistant to many structurally and mechanistically unrelated drugs, the efficacy of chemotherapeutic management of cancer often becomes severely limited. In Multi-Drug Resistance in Cancer, leading researchers in the field provide comprehensive and up-to-date reviews of multidrug resistance mechanisms, from over-expression of ATP-binding cassette drug transporters such as P-glycoprotein, multidrug resistance-associated proteins, and breast cancer resistance protein, to the drug ratio-dependent antagonism and the paradigm of cancer stem cells. The extensive volume also includes strategies to overcome multidrug resistance, from the development of compounds that inhibit drug transporter function to the modulation of transporter expression, as well as techniques for detection and imaging of drug transporters, methods for investigation of drug resistance in animal models, and strategies to evaluate the efficacy of resistance reversal agents. As a volume in the highly successful Methods in Molecular Biology series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and cutting-edge, Multi-Drug Resistance in Cancer offers a state-of-art collection of reviews and methods for both basic and clinician investigators who are interested in the vital study of cancer multi-drug resistance mechanisms and reversal strategies
Member of
Cataloging source
index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Series statement
  • Springer Protocols
  • Methods in molecular biology,
Series volume
Multi-drug resistance in cancer, edited by Jun Zhou
Multi-drug resistance in cancer, edited by Jun Zhou
Title from PDF title page (viewed Dec. 9, 2009)
Related Contributor
Related Location
Related Agents
Related Authorities
Related Subjects
Related Items
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
Carrier MARC source
Content category
Content type code
Content type MARC source
Multidrug resistance in cancer / Bruce C. Baguley --Multidrug resistance in oncology and beyond : from imaging of drug efflux pumps to cellular drug targets / Wouter B. Nagengast [and others] -- Studying drug resistance using genetically engineered mouse models for breast cancer / Sven Rottenberg, Marina Pajic, and Jos Jonkers -- Mechanisms of multidrug resistance in cancer / Jean-Pierre Gillet and Michael M. Gottesman -- Molecular mechanisms of drug resistance in single-step and multi-step drug-selected cancer cells / Anna Maria Calcagno and Suresh V. Ambudkar -- Pharmacogenetics of ATP-binding cassette transporters and clinical implications / Ingolf Cascorbi and Sierk Haenisch -- Flow cytometric evaluation of multidrug resistance proteins / Adorjan Aszalos and Barbara J. Taylor -- Targeted chemotherapy in drug-resistant tumors, noninvasive imaging of P-glycoprotein-mediated functional transport in cancer, and emerging role of pgp in neurodagenerative [sic] diseases / Jothilingam Sivapackiam [and others] -- Epigenetic regulation of multidrug resistance 1 gene expression : profiling CpG methylation status using bisulphite sequencing / Emma K. Baker and Assam El-Osta -- Expression and function of P-glycoprotein in normal tissues : effect on pharmacokinetics / Frantisek Staud [and others] -- Molecular mechanism of ATP-dependent solute transport by multidrug resistance-associated protein 1 / Xiu-bao Chang -- Impact of breast cancer resistance protein on cancer treatment outcomes / Douglas D. Ross and Takeo Nakanishi -- Drug ratio-dependent antagonism : a new category of multidrug resistance and strategies for its circumvention / Troy O. Harasym, Barry D. Liboiron, and Lawrence D. Mayer -- Reversing agents for ATP-binding cassette drug transporters / Chow H. Lee -- Overcoming multidrug resistance in cancer : clinical studies of P-glycoprotein inhibitors / Helen M. Coley -- Pharmacokinetic and pharmacodynamic implications of P-glycoprotein modulation / Jeannie M. Padowski and Gary M. Pollack -- Examination of CYP3A and P-glycoprotein-mediated drug-drug interactions using animal models / Punit H. Marathe and A. David Rodrigues -- Generating inhibitors of P-glycoprotein : where to, now? / Emily Crowley, Christopher A. McDevitt, and Richard Callaghan -- Immunosuppressors as multidrug resistance reversal agents / Hamid Morjani and Claudie Madoulet -- Overcoming multidrug resistance by RNA interference / Alexandra Stege, Andrea Krühn, and Hermann Lage -- Circumventing tumor resistance to chemotherapy by nanotechnology / Xing-Jie Liang [and others]
{'f': ''}
1 online resource (xi, 492 pages)
Form of item
Media category
Media MARC source
Media type code
Other physical details
illustrations (some color).
unknown sound
Specific material designation

Library Locations

    • Folsom LibraryBorrow it
      110 8th St, Troy, NY, 12180, US
      42.729766 -73.682577
Processing Feedback ...