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The Resource Mitochondrial DNA and Diseases, edited by Hongzhi Sun, Xiangdong Wang, (electronic resource)

Mitochondrial DNA and Diseases, edited by Hongzhi Sun, Xiangdong Wang, (electronic resource)

Label
Mitochondrial DNA and Diseases
Title
Mitochondrial DNA and Diseases
Statement of responsibility
edited by Hongzhi Sun, Xiangdong Wang
Contributor
Editor
Subject
Language
eng
Summary
The book describes molecular principles and mechanisms by which mitochondrial DNA (mtDNA) can drive the occurrence of diseases and the latest understanding of mtDNA biology. The book explores roles of mtDNA mutation and genetic changes in cancer, with a special focus on lung cancer, and the significance of approach, application, and bioethics of mtDNA sequencing.  Authors made a great effort to overview roles of mtDNA signaling pathways, base excision repair, methylation, USP30-mediated regulation, mitochondrial ribosome, autophagy pathways, or ROS-dependent signaling in the pathogenesis, diagnosis, prevention and treatment of diseases. It also demonstrates the importance of basic mitochondrial genetics and the relationship between mutations and disease phenotypes and ageing. This book covers not only the basic information of mtDNA, the relationship of mtDNA and disease, but also mtDNA in stem cell and mitochondria and metabolism etc. The book is written for biological and clinical students and researchers in the field of mtDNA{u2013}associated diseases
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Is part of
Image bit depth
0
Literary form
non fiction
Series statement
Advances in Experimental Medicine and Biology,
Series volume
1038
Mitochondrial DNA and Diseases, edited by Hongzhi Sun, Xiangdong Wang, (electronic resource)
Label
Mitochondrial DNA and Diseases, edited by Hongzhi Sun, Xiangdong Wang, (electronic resource)
Link
http://libproxy.rpi.edu/login?url=http://dx.doi.org/10.1007/978-981-10-6674-0
Publication
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Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
How far can mitochondrial DNA drive the disease? -- Mitochondrial DNA in lung cancer -- Approach, application and bioethics of mtDNA sequencing in cancer -- Roles of mitochondrial DNA signaling in immune responses -- Mitochondrial DNA in Telocytes -- Roles of mitochondrial DNA in energy metabolism -- The role of base excision repair in maintaining mitochondrial DNA stability.- Is mitochondrial cell fragility a cell weakness? -- Mitochondrial DNA methylation and related disease -- Beyond deubiquitylation: USP30-mediated regulation of mitochondrial homeostasis -- Metabolic regulation in mitochondria and drug resistance.- Mitochondrial Lon Protease and Cancer -- Regulatory roles of mitochondrial ribosome in lung diseases and single cell biology.-Epithelial mitochondrial dysfunction in lung disease
http://library.link/vocab/cover_art
https://contentcafe2.btol.com/ContentCafe/Jacket.aspx?Return=1&Type=S&Value=9789811066740&userID=ebsco-test&password=ebsco-test
Dimensions
unknown
http://library.link/vocab/discovery_link
{'f': 'http://opac.lib.rpi.edu/record=b4380224'}
Extent
VII, 230 p. 89 illus., 62 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9789811066740
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote

Library Locations

    • Folsom LibraryBorrow it
      110 8th St, Troy, NY, 12180, US
      42.729766 -73.682577
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