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The Resource MRI Contrast Agents : From Molecules to Particles

MRI Contrast Agents : From Molecules to Particles

Label
MRI Contrast Agents : From Molecules to Particles
Title
MRI Contrast Agents
Title remainder
From Molecules to Particles
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Contributor
Subject
Language
eng
Member of
Cataloging source
MiAaPQ
Literary form
non fiction
Nature of contents
dictionaries
Series statement
SpringerBriefs in Applied Sciences and Technology Ser
MRI Contrast Agents : From Molecules to Particles
Label
MRI Contrast Agents : From Molecules to Particles
Link
http://libproxy.rpi.edu/login?url=https://ebookcentral.proquest.com/lib/rpi/detail.action?docID=4733255
Publication
Copyright
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Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
  • Contents -- 1 Interest of Nanomaterials in Medicine -- Abstract -- References -- 2 Magnetic Properties -- Abstract -- 2.1 Diamagnetic Substances -- 2.2 Paramagnetic Substances -- 2.3 Ferromagnetic Substances -- 2.4 Ferrimagnetic Substances -- 2.5 Antiferromagnetic Substances -- 2.6 Superparamagnetic Substances -- References -- 3 Imaging Probes -- Abstract -- 3.1 Magnetic Resonance Imaging (MRI) -- 3.1.1 Classical Description of NMR-Description on the Macroscopic Scale -- 3.1.2 NMR Signal Acquisition -- 3.1.3 Principle of MRI -- 3.1.3.1 Spatial Coding -- 3.1.3.2 Excitation Sequence -- 3.1.3.3 Contrast in MRI -- 3.2 MRI Contrast Agents -- References -- 4 Paramagnetic Gadolinium Complexes -- Abstract -- 4.1 Relaxation Mechanims of Gadolinium Complexes -- 4.1.1 Innersphere Mechanism -- 4.1.2 Outer-Sphere Mechanism -- 4.1.3 Second-Sphere Mechanism -- 4.1.4 Influence of the Different Parameters on the Innersphere and Outersphere Contributions -- 4.1.4.1 Innersphere Contribution -- 4.1.4.2 Outersphere Contribution -- 4.1.4.3 NMRD Profiles -- 4.2 Different Classes of Gadolinium Based MRI Contrast Agents -- 4.2.1 Vascular Contrast Agents -- 4.2.2 Smart Contrast Agents -- 4.2.2.1 PH Sensitive -- 4.2.2.2 Metal Sensitives -- 4.2.2.3 Enzyme-Activated Contrast Agents -- 4.2.2.4 pO2 -- 4.2.3 Specific Contrast Agents for Molecular Imaging -- 4.2.4 How to Obtain High Relaxivity with Paramagnetic Gd-Derivatives by Increasing xR -- 4.2.5 PARACEST Agents -- References -- 5 Superparamagnetic Iron Oxide Nanoparticles -- Abstract -- 5.1 Superparamgnetic Properties of Iron Oxide Nanoparticles -- 5.1.1 Relaxometric Properties -- 5.1.1.1 Relaxation Processes of Single Domain Iron Oxide Nanoparticles -- 5.1.1.2 Superparamagnetic Relaxation: Theoretical Model -- 5.1.1.3 Nuclear Magnetic Resonance Dispersion Profiles (NMRD) -- 5.2 Synthesis of Magnetic Nanoparticles
  • 5.2.1 Coprecipitation Method -- 5.2.2 Hydothermal Method -- 5.2.3 Thermal Decomposition Method -- 5.2.4 Sol-Gel Methods -- 5.2.5 Microemulsions -- 5.2.6 Polyol Methods -- 5.2.7 Electrochemical Methods -- 5.2.8 Aerosol/Vapor Method -- 5.2.9 Sonolysis/Thermolysis -- 5.3 Stabilization of Nanoparticle Suspensions -- 5.3.1 Stability of Charged Nanoparticles -- 5.3.2 Steric Stabilization -- 5.3.3 The Surface of Iron Oxide Nanoparticles -- 5.3.4 Stabilization Strategies -- 5.3.4.1 Silica -- 5.3.4.2 Polymers -- 5.3.4.3 Small Organic Molecules -- 5.3.4.4 Biological Molecules -- 5.3.5 Recent Advances on the Stabilization of Hydrophobic Iron Oxide Nanoparticles -- 5.3.5.1 Stabilization by Ligand Addition -- Polymers -- Alkylammonium Salts -- Lipids -- 5.3.5.2 Stabilization by Ligand Exchange -- Small Charged Molecules -- Polymers -- Silica -- References -- 6 MRI Applications: Classification According to Their Biodistribution -- Abstract -- 6.1 Non-specific Agents (Interstitial Diffusion of Gadolinium Complexes) -- 6.1.1 Toxicity of Free Gadolinium and Gd-Complexes -- 6.1.2 NSF Disease [7-14] -- 6.2 Hepatic Agents -- 6.2.1 Gadolinium Complexes with Biliary Excretion: Gd-EOB-DTPA and Gd-BOPTA -- 6.2.2 Superparamagnetic Iron Oxide Nanoparticles as Specific Agents of Kupffer Cells -- 6.2.3 Contrast Agents for Lymphatic System -- 6.3 Vascular Contrast Agents -- 6.3.1 Superparamagnetic Nanoparticles -- 6.3.2 Macromolecular Contrast Agents (Albumin-Dextran, Polylysine-Gd-DTPA) -- 6.3.3 Applications -- 6.4 Conclusions -- References
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{'f': 'http://opac.lib.rpi.edu/record=b4386479'}
Extent
1 online resource (128 pages)
Form of item
online
Isbn
9789811025297
Media category
computer
Media MARC source
rdamedia
Media type code
c
Sound
unknown sound
Specific material designation
remote

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