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The Resource Liver Disease in Clinical Practice

Liver Disease in Clinical Practice

Label
Liver Disease in Clinical Practice
Title
Liver Disease in Clinical Practice
Creator
Subject
Language
eng
Member of
Cataloging source
MiAaPQ
Literary form
non fiction
Nature of contents
dictionaries
Series statement
In Clinical Practice
Liver Disease in Clinical Practice
Label
Liver Disease in Clinical Practice
Link
http://libproxy.rpi.edu/login?url=https://ebookcentral.proquest.com/lib/rpi/detail.action?docID=4768062
Publication
Copyright
Related Contributor
Related Location
Related Agents
Related Authorities
Related Subjects
Related Items
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
  • Foreword -- Contents -- Contributors -- Part I: Clinical Manifestations and Approach to Liver Disease -- Chapter 1: Assessment of Liver Function -- Case Study -- Questions -- An Overview of Anatomy and Functions of the Liver -- Metabolic -- Immunologic -- Interpretation of Liver Function Tests -- Tests of Hepatocellular Damage -- Serum Aminotransferases (ALT and AST) [3] -- Alkaline Phosphatase (ALP) [6] -- Isolated GGT Elevation [6] -- Bilirubin -- Test of Liver Synthetic Function -- Prothrombin Time -- Albumin -- Parenchymal Liver Screen -- Liver Fibrosis -- Answer to Question 1 -- Answer to Question 2 -- Answer to Question 3 -- References -- Chapter 2: Liver Decompensation and Acute on Chronic Liver Failure -- Case Study -- Introduction -- ACLF and Prognostication Models -- Pathogenesis of Acute-on-Chronic Liver Failure -- "The Gut-Liver Immune Axis" -- Circulatory Dysfunction -- Cardiac Dysfunction (Cirrhotic Cardiomyopathy) -- Renal Failure -- Adrenal Dysfunction (Hepatoadrenal Dysfunction) -- Principles of Management of Liver Decompensation -- General Approach to Management -- Variceal Haemorrhage -- Ascites -- Encephalopathy -- Alcoholic Hepatitis -- Infections and Sepsis -- Renal Failure and Hepatorenal Syndrome -- Adrenal Failure -- Coagulopathy -- Summary -- Case Study Answers -- References -- Chapter 3: Portal Hypertension: Varices -- Case -- Pathophysiology of Portal Hypertension -- Classification of Portal Hypertension -- Portal Hypertension Due to Cirrhosis -- Development of Varices -- Manifestations of Varices -- Diagnosis of Varices -- Surveillance of Varices -- Treatment -- Treatment to Prevent Development of Varices -- Prophylactic Treatment to Prevent First Variceal Haemorrhage -- Treatment of Variceal Haemorrhage -- Medical Therapy -- Endoscopic Variceal Ligation -- Failure of First-Line Therapy -- TIPSS Placement
  • Secondary Prophylaxis -- Gastric Varices -- Questions -- References -- Chapter 4: Hepatic Encephalopathy -- Case Study -- Introduction -- Definitions and Classification of HE -- Pathophysiology of HE -- Investigations and Diagnosis -- Management of HE -- HE and End-of-Life Care -- Nutrition -- Non-absorbable Disaccharides and Probiotics -- Neomycin and Rifaximin -- Alternative and Novel Therapies -- Answers to Case Study -- Key References -- Chapter 5: Nutritional Management of End-Stage Liver Disease -- Introduction -- Nutritional Assessment Tools -- Contributing Factors to Liver Disease-Related Malnutrition -- Decreased Intake -- Malabsorption -- Metabolic Factors -- Sarcopenia: The Predominant Feature of Malnutrition in Cirrhosis -- Malnutrition and Prognosis -- Nutritional Interventions in Liver Disease -- Oral Diet Recommendations -- Artificial Enteral Nutrition Recommendations -- Parenteral Nutrition Recommendations -- Summary -- References -- Part II: Liver Diseases of Lifestyle, Genes and Metabolism -- Chapter 6: Alcoholic Hepatitis -- Questions on Alcoholic Hepatitis -- Introduction -- Pathophysiology -- Clinical Presentation -- Diagnostic Tests -- Assessing Disease Severity in Alcoholic Hepatitis -- Maddrey's Discriminant Function -- Glasgow Alcoholic Hepatitis Score -- Model of End-Stage Liver Disease (MELD) Score -- Management of Alcoholic Hepatitis -- General Measures -- Alcohol Abstinence -- Prevention and Treatment of Alcohol Withdrawal -- Hydration and Nutritional Support -- Infection Surveillance and Treatment -- Prophylaxis Against Gastric Mucosal Bleeding -- Specific Pharmacological Therapies -- Corticosteroids -- Pentoxifylline -- Other Pharmacological Treatments -- Liver Transplantation -- Conclusion -- Questions on Alcoholic Hepatitis -- References -- Chapter 7: Non-alcoholic Fatty Liver Disease -- Case Study -- Introduction
  • Pathophysiology -- Natural History -- Making the Diagnosis of NAFLD -- Clinical History and Examination -- Blood Tests -- Imaging -- Non-invasive Markers of Fibrosis in NAFLD -- Scoring Systems -- Transient Elastography -- Non-invasive Markers for NASH -- The Role of Liver Biopsy -- Management -- Weight Loss and Lifestyle Modification -- Interventions for Metabolic Syndrome ± Secondary Benefits on the Liver -- Liver-Specific Agents -- Monitoring Cirrhosis, Liver Transplantation and the Multidisciplinary Approach -- Future Directions -- Answers -- References -- Chapter 8: Genetic Haemochromatosis -- Case Study -- Introduction -- Background -- Iron Pathophysiology -- Disease Expression -- Diagnosis -- Treatment -- Unusual Variants -- Conclusion -- Answers to Case Study -- References -- Chapter 9: The Orphan liver Diseases -- Case -- Questions -- Porphyria -- Overview -- Classification of Porphyrias -- Alpha-1-Antitrypsin Deficiency -- Overview -- Genetics and Epidemiology -- Clinical Presentation -- Diagnosis -- Treatment -- Cystic Fibrosis and Liver Disease -- Overview -- Investigations -- Treatment -- Answers to Case Study Questions -- References -- Part III: Viral Liver Disease -- Chapter 10: Chronic Hepatitis B -- Case Study -- Introduction -- Epidemiology -- Preventative Measures -- Screening -- Immunisation -- Diagnosis and Disease Workup -- Virology -- Structure -- Viral Replication -- Natural History and Immunology -- Acute HBV Infection -- Phases of Chronic HBV Infection -- Management of Chronic Hepatitis B Infection -- Nucleos(t)ide Analogues (NUCs) -- Pegylated-Interferon (Peg-IFN) -- Patient Selection: Who to Treat? -- e-Antigen Positive -- e-Antigen Negative -- Special Populations -- Cirrhotic -- Immunosuppressed -- Pregnancy -- Future Therapies -- Conclusion -- Answers to Case Study -- References -- Chapter 11: Chronic Hepatitis C
  • Case Study -- Questions -- Background -- Presentation -- Investigation -- Management -- Interferon -- Directly Acting Antiviral Agents (DAAs) -- Answers to Questions -- References -- Part IV: Immune Mediated Liver Disease -- Chapter 12: Autoimmune Hepatitis and Crossover Syndromes -- Case History -- Question 1 -- Question 2 -- Question 3 -- Introduction -- Epidemiology -- Aetiology and Pathogenesis -- Pathology -- Clinical Features -- Differential Diagnosis -- Diagnosis -- Biochemical -- Immunological -- Other Investigations -- Scoring Systems -- Management -- Who Should Be Treated? -- Pharmacological Treatment -- Other Treatment Considerations -- Outcome and Prognosis -- Liver Transplantation -- Special Circumstances -- Pregnancy -- Crossover Syndromes -- PBC-AIH Overlap -- PSC-AIH Overlap -- Summary -- Case history -- Question 1 -- Answer -- Question 2 -- Answer -- Question 3 -- Answer -- Bibliography -- Chapter 13: Primary Biliary Cholangitis -- Questions -- Introduction -- Pathophysiology -- Autoantibodies in PBC -- Natural History of PBC -- AMA-Positive Patients Without Other Features of PBC -- AMA-Negative PBC -- Prognostic Predictors and Prognostic Scoring Systems in PBC -- Clinical Manifestations of PBC -- Fatigue -- Pruritus -- Diagnosis and Histological Staging of PBC -- Treatment of PBC -- Ursodeoxycholic Acid -- Budesonide -- Fibric Acid Derivatives -- Other Treatments for PBC -- Obeticholic Acid -- Other Treatments -- Answers to Questions -- Key References -- Chapter 14: Primary Sclerosing Cholangitis -- Case Study -- Introduction -- Pathogenesis -- Presentation -- Diagnosis -- Investigations -- Bloods -- Imaging -- Biopsy -- Differential Diagnosis -- Management -- Medical Therapy -- Symptom Control -- Complications -- Disease Progression: Prognostic Scores and Stratification -- Transplantation -- Special Situations -- Overlap
  • Paediatric PSC -- PSC: IBD -- Case and Questions -- References -- Part V: Areas of Special Consideration -- Chapter 15: Pregnancy and Liver Disease -- Case Study -- Questions -- Introduction -- Normal Physiology in Pregnancy -- Pregnancy-Related Liver Diseases -- Hyperemesis Gravidarum -- Intrahepatic Cholestasis of Pregnancy -- Pre-eclampsia/Eclampsia/HELLP Syndrome -- Acute Fatty Liver of Pregnancy (AFLP) -- Hepatic Haemorrhage and Rupture -- Nonpregnancy-Related Liver Diseases -- Cirrhosis and Portal Hypertension -- Hepatitis B and C Virus Infection and Pregnancy -- Autoimmune Hepatitis and Pregnancy -- Liver Transplantation -- Liver Disease De Novo in Pregnancy -- Acute Viral Infections and Pregnancy -- Pregnancy and Thrombosis -- Gallstones in Pregnancy -- Summary -- Answers to Case Study -- References -- Chapter 16: Diagnosis and Management of Hepatocellular Carcinoma -- Case Study -- Introduction -- Diagnosis of Hepatocellular Carcinoma -- Current Treatment Modalities for Treatment of Hepatocellular Carcinoma -- The Role of HCC Surveillance in at Risk Patients -- The Role of Liver Transplantation in the Management of HCC -- The Role of Downstaging -- Treatment on the Waiting List -- Liver Transplantation as Salvage Therapy -- Delisting HCC Patients -- Improving Existing Therapies -- Future Direction of Systemic Therapy -- Getting More from Sorafenib -- New Drugs and New Targets -- Conclusion -- Answers to Questions -- References -- Chapter 17: Liver Transplantation -- Case Study -- Questions -- Introduction -- Candidates -- Indications for Liver Transplantation -- Prognostic Scoring Systems for End-Stage Liver Disease -- The Model of End-Stage Liver Disease (MELD) -- The United Kingdom Model for End-Stage Liver Disease (UKELD) -- Super-Urgent LT -- Malignant Liver Disease -- Absolute and Relative Contraindications to LT
  • Pre-transplant Assessment
http://library.link/vocab/cover_art
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unknown
http://library.link/vocab/discovery_link
{'f': 'http://opac.lib.rpi.edu/record=b4387044'}
Extent
1 online resource (381 pages)
Form of item
online
Isbn
9783319431260
Media category
computer
Media MARC source
rdamedia
Media type code
c
Sound
unknown sound
Specific material designation
remote

Library Locations

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