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The Resource Lipid Oxidation in Health and Disease

Lipid Oxidation in Health and Disease

Label
Lipid Oxidation in Health and Disease
Title
Lipid Oxidation in Health and Disease
Creator
Contributor
Subject
Language
eng
Summary
Oxidative modification of lipids and phospholipids-including radical damage, halogenation, and nitration-result in significant changes to the chemical properties of the molecules, which in turn have a major effect on their biochemical functions. Lipid oxidation has long been regarded as a deleterious process responsible for lipid rancidity, loss of function, and generation of toxic products. However in recent years, research has also focused on the non-detrimental physiological and pathological effects of these chemical reactions. Lipid Oxidation in Health and Disease provides an up-to-date review of the role of oxidized lipid products in physiological and pathophysiological processes. Covering the diverse topics that contribute to research in this important field, this book explores: The mechanisms of lipid oxidation, both enzymatic and non-enzymatic Antioxidant defenses and lipid oxidation Lipid oxidation products and cell signaling The roles of oxidized lipids in specific diseases-including cardiovascular, neurodegenerative, and metabolic disorders, as well as in cancer Drug targeting and the therapeutic potential of oxidized lipids Accurate measurement of the formation of lipid oxidation products and investigation of their biological effects and roles in disease are critical to biomedical science and new targeted therapeutics. Written by acknowledged experts in the field, this book provides a broad survey of both established knowledge and recent findings on the action of oxidized lipid products on cell signaling and gene expression in health and disease
Member of
Cataloging source
MiAaPQ
Literary form
non fiction
Nature of contents
dictionaries
Series statement
Oxidative Stress and Disease
Lipid Oxidation in Health and Disease
Label
Lipid Oxidation in Health and Disease
Link
http://libproxy.rpi.edu/login?url=https://ebookcentral.proquest.com/lib/rpi/detail.action?docID=1822750
Publication
Copyright
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Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Front Cover -- Contents -- Series Preface -- Editors -- Contributors -- Introduction -- Chapter 1: An Introduction to Redox Balance and Lipid Oxidation -- Chapter 2: Nonenzymatic Mechanisms of Lipid Oxidation -- Chapter 3: Enzymatic Oxidation of Polyunsaturated Fatty Acids -- Chapter 4: Halogenated Lipids : Products of Peroxidase-Derived Reactive Halogenating Species Targeting Conventional Lipids -- Chapter 5: Formation of Nitrated Lipids and Their Biological Relevance -- Chapter 6: Protein Lipoxidation -- Chapter 7: Analysis of Lipid Peroxidation Products in Health and Disease -- Chapter 8: Oxidized Lipids as Damage-Associated Molecular Patterns in Inflammatory Responses -- Chapter 9: Formation and Beneficial Roles of Polyunsaturated Lipid Mediators : Lipoxins, Resolvins, Protectins, and Maresins -- Chapter 10: Pro- and Anti-Inflammatory Action of Oxidized Phospholipids -- Chapter 11: Modulation of Toll-Like Receptor Signaling by Oxidized Phospholipids -- Chapter 12: Dietary Oxidized Lipids as Regulators of Intracellular Signaling Pathways : PPAR and NF-mB -- Chapter 13: Oxidized and Nitrated Lipid Interactions with the Keap1-Nrf2 Pathway -- Chapter 14: Role of Oxidized Phospholipids in Cardiovascular Disease -- Chapter 15: Cholesterol Oxidation Products in the Initiation, Progression, and Fate of Atherosclerotic Lesions -- Chapter 16: Lipid Peroxidation and Age-Related Neurodegenerative Disorders -- Chapter 17: Association of Oxidative Stress and Lipids with Risk Factors of Metabolic Syndrome -- Chapter 18: Oxidized Lipid Products and Carcinogenesis -- Back Cover
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unknown
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{'f': 'http://opac.lib.rpi.edu/record=b3737074'}
Edition
1st ed.
Extent
1 online resource (428 pages)
Form of item
online
Isbn
9781482202861
Media category
computer
Media MARC source
rdamedia
Media type code
c
Sound
unknown sound
Specific material designation
remote

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