Coverart for item
The Resource Impact of Survivin Acetylation on its Biological Function, by David Dannheisig, (electronic resource)

Impact of Survivin Acetylation on its Biological Function, by David Dannheisig, (electronic resource)

Label
Impact of Survivin Acetylation on its Biological Function
Title
Impact of Survivin Acetylation on its Biological Function
Statement of responsibility
by David Dannheisig
Creator
Contributor
Author
Subject
Language
eng
Summary
In his research, David Dannheisig investigates the influence of lysine129 acetylation on the biological function of survivin including alteration of nucleocytoplasmic shuttling as well as dimerization behavior. Since survivin participates in two major hallmarks of oncogenesis, namely cell death inhibition and chromosomal segregation during the cell cycle, it reflects a valuable target in cancer therapy and research. The author establishes proximity-dependent, fluorescence-microscopic methods to quantify the interaction of survivin with the export receptor Crm1 as well as the homodimerization itself. In the future, those systems can be used to examine the feasible effect of chemical modulators which are targeting these interactions in a cellular background. The outcome achieved is an essential step towards the enhancement of potential cancer therapies. Contents Apoptosis {u2013} The Programmed Suicide Cancer {u2013} The Enemy Inside Nucleocytoplasmic Transport{u2013} Cellular Navigation Biological Function of Survivin Protein modification {u2013} Make-Up for Proteins Cell cycle {u2013} Virchow{u2019}s Heritage Target Groups Lecturers, students and researchers in the biological-medical sector Practitioners in the fields of molecular biology, cell biology, fluorescence microscopy, medical biology, protein interaction studies The Author David Dannheisig currently is a student of the International Graduate School in Molecular Medicine (IGradU) pursuing his PhD (Dr. rer. nat) degree at the Institute of Biochemistry and Molecular Biology (iBMB) at Ulm University, Germany
Member of
Is part of
Image bit depth
0
Literary form
non fiction
Series statement
BestMasters
Impact of Survivin Acetylation on its Biological Function, by David Dannheisig, (electronic resource)
Label
Impact of Survivin Acetylation on its Biological Function, by David Dannheisig, (electronic resource)
Link
http://libproxy.rpi.edu/login?url=http://dx.doi.org/10.1007/978-3-658-18623-4
Publication
Related Contributor
Related Location
Related Agents
Related Authorities
Related Subjects
Related Items
Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Apoptosis {u2013} The Programmed Suicide -- Cancer {u2013} The Enemy Inside -- Nucleocytoplasmic Transport{u2013} Cellular Navigation -- Biological Function of Survivin -- Protein modification {u2013} Make-Up for Proteins -- Cell cycle {u2013} Virchow{u2019}s Heritage
http://library.link/vocab/cover_art
https://contentcafe2.btol.com/ContentCafe/Jacket.aspx?Return=1&Type=S&Value=9783658186234&userID=ebsco-test&password=ebsco-test
Dimensions
unknown
http://library.link/vocab/discovery_link
{'f': 'http://opac.lib.rpi.edu/record=b4258239'}
Extent
XXIII, 104 p. 41 illus., 10 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9783658186234
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote

Library Locations

    • Folsom LibraryBorrow it
      110 8th St, Troy, NY, 12180, US
      42.729766 -73.682577
Processing Feedback ...