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The Resource Hot-melt extrusion : pharmaceutical applications, edited by Dennis Douroumis, (electronic resource)

Hot-melt extrusion : pharmaceutical applications, edited by Dennis Douroumis, (electronic resource)

Label
Hot-melt extrusion : pharmaceutical applications
Title
Hot-melt extrusion
Title remainder
pharmaceutical applications
Statement of responsibility
edited by Dennis Douroumis
Contributor
Subject
Language
eng
Summary
"Hot-melt extrusion (HME) - melting a substance and forcing it through an orifice under controlled conditions to form a new material - is an emerging processing technology in the pharmaceutical industry for the preparation of various dosage forms and drug delivery systems, for example granules and sustained release tablets.Hot-Melt Extrusion: Pharmaceutical Applications covers the main instrumentation, operation principles and theoretical background of HME. It then focuses on HME drug delivery systems, dosage forms and clinical studies (including pharmacokinetics and bioavailability) of HME products. Finally, the book includes some recent and novel HME applications, scale -up considerations and regulatory issues. Topics covered include: principles and die design of single screw extrusion twin screw extrusion techniques and practices in the laboratory and on production scale HME developments for the pharmaceutical industry solubility parameters for prediction of drug/polymer miscibility in HME formulations the influence of plasticizers in HME applications of polymethacrylate polymers in HME HME of ethylcellulose, hypromellose, and polyethylene oxide bioadhesion properties of polymeric films produced by HME taste masking using HME clinical studies, bioavailability and pharmacokinetics of HME products injection moulding and HME processing for pharmaceutical materials laminar dispersive & distributive mixing with dissolution and applications to HME technological considerations related to scale-up of HME processes devices and implant systems by HME an FDA perspective on HME product and process understanding improved process understanding and control of an HME process with near-infrared spectroscopy Hot-Melt Extrusion: Pharmaceutical Applications is an essential multidisciplinary guide to the emerging pharmaceutical uses of this processing technology for researchers in academia and industry working in drug formulation and delivery, pharmaceutical engineering and processing, and polymers and materials science"--
Assigning source
Provided by publisher
Cataloging source
MiAaPQ
Illustrations
  • illustrations
  • plates
Index
index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Series statement
Advances in pharmaceutical technology
Hot-melt extrusion : pharmaceutical applications, edited by Dennis Douroumis, (electronic resource)
Label
Hot-melt extrusion : pharmaceutical applications, edited by Dennis Douroumis, (electronic resource)
Link
http://libproxy.rpi.edu/login?url=https://ebookcentral.proquest.com/lib/connectny/detail.action?docID=882714
Publication
Related Contributor
Related Location
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Bibliography note
Includes bibliographical references and index
Color
multicolored
Dimensions
unknown
http://library.link/vocab/discovery_link
{'f': 'http://opac.lib.rpi.edu/record=b4046544'}
Extent
xviii, 364 p., [16] p. of plates
Form of item
  • online
  • electronic
Other physical details
ill. (some col.).
Reproduction note
Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries.
Specific material designation
remote

Library Locations

    • Folsom LibraryBorrow it
      110 8th St, Troy, NY, 12180, US
      42.729766 -73.682577
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