The Resource Genotoxicity assessment : methods and protocols, edited by Alok Shawan, Mahima Bajpayee
Genotoxicity assessment : methods and protocols, edited by Alok Shawan, Mahima Bajpayee
- Summary
- Genetic toxicology is recognized by geneticists and researchers concerned with the genetic impact of man-made chemicals. In Genotoxicity Assessment: Methods and Protocols, expert researchers in the field provide comprehensive genetictoxicology protocols. These include in vitro and in vivo protocols on mutation assays, cytogenetic techniques, and primary DNA damage, assays in alternate to animal models, and updated ICH guidelines. Written in the highly successfulMethods in Molecular Biology series format, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as key tips ontroubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Genotoxicity Assessment: Methods and Protocols seeks to aid research students and scientists working in regulatory toxicology as well as biomedical, biochemical and pharmaceutical sciences
- Language
- eng
- Extent
- 1 online resource (xv, 463 pages)
- Contents
-
- In vivo cII, gpt, and spi- gene mutation assays in transgenic mice and rats
- Mugimane G. Manjanatha [and others]
- In vitro cytogenetic assays : chromosomal aberrations and micronucleus tests
- Julian Laubenthal [and others]
- Comet assay : assessment of in vitro and in vivo DNA damage
- Mahima Bajpayee, Ashutosh Kumar, and Alok Dhawan
- Comet assay in human biomonitoring
- Diana Anderson, Alok Dhawan, and Julian Laubenthal
- Comet assay in marine animals
- Giada Frenzilli and Brett P. Lyons
- Bacterial mutation assays
- Unscheduled DNA synthesis (UDS) test with mammalian liver cells in vivo
- Fabrice Nesslany
- 32P-postlabeling analysis of DNA adducts
- Heinz H. Schmeiser, Marie Stiborova, and Volker M. Arlt
- Micronucleus assay with tetrad cells of tradescantia
- Miroslav Mišík [and others]
- Wing-spot and the comet tests as useful assays detecting genotoxicity in Drosophila
- Ricard Marcos and Erico R. Carmona
- Genotoxicity guidelines recommended by International Conference of Harmonization (ICH)
- Gireesh H. Kamath and K.S. Rao
- Errol Zeiger
- In vitro mouse lymphoma (L5178Y Tk+/- -3.7.2C) forward mutation assay
- Melissa R. Schisler, Martha M. Moore, and B. Bhaskar Gollapudi
- Erythrocyte-based pig-a gene mutation assay
- Jeffrey C. Bemis, Nikki E. Hall, and Stephen D. Dertinger
- Detection of in vivo mutation in the Hprt and pig-a genes of rat lymphocytes
- Vasily N. Dobrovolsky [and others]
- Isbn
- 9781627035293
- Label
- Genotoxicity assessment : methods and protocols
- Title
- Genotoxicity assessment
- Title remainder
- methods and protocols
- Statement of responsibility
- edited by Alok Shawan, Mahima Bajpayee
- Language
- eng
- Summary
- Genetic toxicology is recognized by geneticists and researchers concerned with the genetic impact of man-made chemicals. In Genotoxicity Assessment: Methods and Protocols, expert researchers in the field provide comprehensive genetictoxicology protocols. These include in vitro and in vivo protocols on mutation assays, cytogenetic techniques, and primary DNA damage, assays in alternate to animal models, and updated ICH guidelines. Written in the highly successfulMethods in Molecular Biology series format, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as key tips ontroubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Genotoxicity Assessment: Methods and Protocols seeks to aid research students and scientists working in regulatory toxicology as well as biomedical, biochemical and pharmaceutical sciences
- Cataloging source
- GW5XE
- Illustrations
- illustrations
- Index
- index present
- Literary form
- non fiction
- Nature of contents
-
- dictionaries
- bibliography
- Series statement
- Methods in molecular biology
- Series volume
- 1044
- Label
- Genotoxicity assessment : methods and protocols, edited by Alok Shawan, Mahima Bajpayee
- Antecedent source
- unknown
- Bibliography note
- Includes bibliographical references and index
- Carrier category
- online resource
- Carrier category code
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
- txt
- Content type MARC source
- rdacontent
- Contents
-
- In vivo cII, gpt, and spi- gene mutation assays in transgenic mice and rats
- Mugimane G. Manjanatha [and others]
- In vitro cytogenetic assays : chromosomal aberrations and micronucleus tests
- Julian Laubenthal [and others]
- Comet assay : assessment of in vitro and in vivo DNA damage
- Mahima Bajpayee, Ashutosh Kumar, and Alok Dhawan
- Comet assay in human biomonitoring
- Diana Anderson, Alok Dhawan, and Julian Laubenthal
- Comet assay in marine animals
- Giada Frenzilli and Brett P. Lyons
- Bacterial mutation assays
- Unscheduled DNA synthesis (UDS) test with mammalian liver cells in vivo
- Fabrice Nesslany
- 32P-postlabeling analysis of DNA adducts
- Heinz H. Schmeiser, Marie Stiborova, and Volker M. Arlt
- Micronucleus assay with tetrad cells of tradescantia
- Miroslav Mišík [and others]
- Wing-spot and the comet tests as useful assays detecting genotoxicity in Drosophila
- Ricard Marcos and Erico R. Carmona
- Genotoxicity guidelines recommended by International Conference of Harmonization (ICH)
- Gireesh H. Kamath and K.S. Rao
- Errol Zeiger
- In vitro mouse lymphoma (L5178Y Tk+/- -3.7.2C) forward mutation assay
- Melissa R. Schisler, Martha M. Moore, and B. Bhaskar Gollapudi
- Erythrocyte-based pig-a gene mutation assay
- Jeffrey C. Bemis, Nikki E. Hall, and Stephen D. Dertinger
- Detection of in vivo mutation in the Hprt and pig-a genes of rat lymphocytes
- Vasily N. Dobrovolsky [and others]
- http://library.link/vocab/cover_art
- https://contentcafe2.btol.com/ContentCafe/Jacket.aspx?Return=1&Type=S&Value=9781627035293&userID=ebsco-test&password=ebsco-test
- Dimensions
- unknown
- http://library.link/vocab/discovery_link
- {'f': 'http://opac.lib.rpi.edu/record=b3415039'}
- Extent
- 1 online resource (xv, 463 pages)
- File format
- unknown
- Form of item
- online
- Isbn
- 9781627035293
- Lccn
- 2013941726
- Level of compression
- unknown
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
- c
- Other physical details
- illustrations (some color).
- Quality assurance targets
- not applicable
- Reformatting quality
- unknown
- Sound
- unknown sound
- Specific material designation
- remote
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.lib.rpi.edu/portal/Genotoxicity-assessment--methods-and-protocols/Ki1TJkQrgU0/" typeof="WorkExample http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.lib.rpi.edu/portal/Genotoxicity-assessment--methods-and-protocols/Ki1TJkQrgU0/">Genotoxicity assessment : methods and protocols, edited by Alok Shawan, Mahima Bajpayee</a></span> - <span property="offers" typeOf="Offer"><span property="offeredBy" typeof="Library ll:Library" resource="http://link.lib.rpi.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.lib.rpi.edu/">Rensselaer Libraries</a></span></span></span></span></div>
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.lib.rpi.edu/portal/Genotoxicity-assessment--methods-and-protocols/Ki1TJkQrgU0/" typeof="WorkExample http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.lib.rpi.edu/portal/Genotoxicity-assessment--methods-and-protocols/Ki1TJkQrgU0/">Genotoxicity assessment : methods and protocols, edited by Alok Shawan, Mahima Bajpayee</a></span> - <span property="offers" typeOf="Offer"><span property="offeredBy" typeof="Library ll:Library" resource="http://link.lib.rpi.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.lib.rpi.edu/">Rensselaer Libraries</a></span></span></span></span></div>
