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The Resource Dual-Mode Electro-photonic Silicon Biosensors, by José Juan Colás, (electronic resource)

Dual-Mode Electro-photonic Silicon Biosensors, by José Juan Colás, (electronic resource)

Label
Dual-Mode Electro-photonic Silicon Biosensors
Title
Dual-Mode Electro-photonic Silicon Biosensors
Statement of responsibility
by José Juan Colás
Creator
Contributor
Author
Subject
Language
eng
Summary
This highly interdisciplinary thesis reports ontwo innovative photonic biosensors that combine multiple simultaneous measurements to provide unique insights into the activity and structure of surface immobilized biological molecules. In addition, it presents a new silicon photonic biosensor that exploits two cascaded resonant sensors to provide two independent measurements of a biological layer immobilized on the surface. By combining these two measurements, it is possible to unambiguously quantify the density and thickness of the molecular layer; here, the approach{u2019}s ability to study molecular conformation and conformational changes in real timeis demonstrated. The electrophotonic biosensor integrates silicon photonics with electrochemistry into a single technology. This multi-modal biosensor provides a number of unique capabilities that extend the functionality of conventional silicon photonics. For example, by combining the complementary information revealed by simultaneous electrochemical and photonic measurements, it is possible to provide unique insights into on-surface electrochemical processes. Furthermore, the ability to create electrochemical reactions directly on the silicon surface provides a novel approach for engineering the chemical functionality of the photonic sensors. The electrophotonic biosensor thus represents a critical advance towards the development of very high-density photonic sensor arrays for multiplexed diagnostics
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0
Literary form
non fiction
Series statement
Springer Theses, Recognizing Outstanding Ph.D. Research,
Dual-Mode Electro-photonic Silicon Biosensors, by José Juan Colás, (electronic resource)
Label
Dual-Mode Electro-photonic Silicon Biosensors, by José Juan Colás, (electronic resource)
Link
http://libproxy.rpi.edu/login?url=http://dx.doi.org/10.1007/978-3-319-60501-2
Publication
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Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Introduction -- Fundamentals of Label-Free Biosensing -- Fabrication and Experimental Techniques -- The Electro-photonic Silicon Biosensor -- Study and Application of Electrografted Layers of Diazonium Ions -- Tailoring Light-matter Interaction for Quanti{uFB01}cation of Biological and Molecular Layers -- Conclusions and Outlook
http://library.link/vocab/cover_art
https://contentcafe2.btol.com/ContentCafe/Jacket.aspx?Return=1&Type=S&Value=9783319605012&userID=ebsco-test&password=ebsco-test
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unknown
http://library.link/vocab/discovery_link
{'f': 'http://opac.lib.rpi.edu/record=b4257921'}
Extent
XV, 149 p. 105 illus., 89 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9783319605012
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote

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