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The Resource Crash Course Haematology and Immunology Updated Edition - E-Book

Crash Course Haematology and Immunology Updated Edition - E-Book

Label
Crash Course Haematology and Immunology Updated Edition - E-Book
Title
Crash Course Haematology and Immunology Updated Edition - E-Book
Creator
Contributor
Subject
Language
eng
Member of
Cataloging source
MiAaPQ
Literary form
non fiction
Nature of contents
dictionaries
Series statement
Crash Course
Crash Course Haematology and Immunology Updated Edition - E-Book
Label
Crash Course Haematology and Immunology Updated Edition - E-Book
Link
http://libproxy.rpi.edu/login?url=https://ebookcentral.proquest.com/lib/rpi/detail.action?docID=3563734
Publication
Copyright
Related Contributor
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Related Agents
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Related Items
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
  • Front Cover -- Haematology and Immunology -- Copyright -- Series editor foreword -- Prefaces -- Acknowledgements -- Contents -- Chapter 1: Principles of haematology -- Overview of haematology-the cell lines -- Haemopoiesis and its regulation -- Sites of haemopoiesis -- Progenitor cells -- Regulation of haemopoiesis -- Bone marrow -- Structure -- Generation of differentiated lymphocytes -- The spleen -- Structure -- Red pulp -- White pulp and marginal zone -- Embryology -- Disorders of the spleen -- Splenomegaly -- Splenic infarction -- Congenital abnormalities -- Rupture of the spleen -- Splenectomy -- Lymphadenopathy -- Chapter 2: Red blood cells and haemoglobin -- Structure and function of erythrocytes -- Erythrocyte structure -- Erythrocyte function -- Gas exchange and transport -- Electrolyte balance -- Erythropoiesis -- Sequence of erythropoiesis -- Ineffective erythropoiesis -- Regulation of erythropoiesis -- Erythropoietin (EPO) -- Control of erythropoietin drive -- Iron and haem metabolism -- Iron metabolism -- Uptake and excretion of iron -- Iron transport and storage proteins -- Iron overload -- Increased absorption -- Iatrogenic causes of increased iron uptake -- Treatment -- Haem metabolism -- Haem biosynthesis -- Haem breakdown -- Haemoglobin -- Structure of haemoglobin -- The genetics of haemoglobin -- Physiological properties of haemoglobin -- The cytoskeleton of the red cell -- Structure -- Integral proteins -- Peripheral proteins -- Surface proteins -- Metabolism of red cells -- Glycolysis and the Embden-Meyerhof pathway -- The Luebering-Rapoport shunt -- The hexose monophosphate shunt -- Prevention of haem oxidation -- Full blood count and reticulocyte count -- Peripheral blood film -- Normal red blood cells -- Chapter 3: Red blood cell disorders -- Anaemia caused by haematinic deficiency -- Iron-deficiency anaemia
  • Anaemia of chronic disease -- Megaloblastic anaemias -- Vitamin B12 deficiency -- Pernicious anaemia -- Folate deficiency -- Anaemia due to increased red-cell destruction (haemolytic anaemias) -- Hereditary red-cell defects -- Cytoskeleton defects -- Hereditary spherocytosis -- Hereditary elliptocytosis -- Enzyme defects -- Pyruvate kinase deficiency -- Glucose-6-phosphate dehydrogenase deficiency -- Other enzyme defects -- Acquired defects of the red cell -- Paroxysmal nocturnal haemoglobinuria (PNH) -- Antibody-mediated red-cell destruction -- Autoimmune haemolytic anaemias -- Alloimmune haemolytic anaemias -- Drug-induced immune haemolytic anaemias -- Other causes of haemolysis -- Haemoglobinopathies -- Thalassaemias -- Ý-Thalassaemia major -- Ý-Thalassaemia minor -- Sickle-cell syndromes -- Investigation of haemoglobinopathies -- Electrophoresis -- Anaemia due to blood loss -- Acute blood loss -- Chronic blood loss -- Marrow defects -- Aplastic anaemia -- Pure red-cell aplasia -- Other forms of marrow failure -- Polycythaemia (erythrocytosis) -- Chapter 4: White blood cells -- Structure and function of the white blood cells -- Lymphocytes -- Appearance and structure -- Location -- Function -- Neutrophils -- Appearance and structure -- Location -- Function -- Monocytes -- Appearance and structure -- Location -- Function -- Eosinophils -- Appearance and structure -- Location -- Function -- Basophils -- Appearance and structure -- Location -- Function -- Differentiation of white cells -- Differential white count -- Reactive proliferation of white cells -- Leucocytosis -- Leucopenia -- Causes of neutropenia and agranulocytosis -- Inadequate granulopoiesis -- Accelerated removal of granulocytes -- Drug-induced neutropenia -- Causes of lymphopenia -- Chapter 5: Haematological malignancies -- Introduction to haematological malignancies
  • Myeloproliferative neoplasms -- Primary thrombocythaemia (essential thrombocythaemia) -- Primary polycythaemia (polycythaemia rubra vera) -- Myelofibrosis -- Myelodysplastic syndromes -- Leukaemia -- Features common to leukaemias -- Acute myeloid leukaemia -- Chronic myeloid leukaemia -- Acute lymphoblastic leukaemia -- Chronic lymphocytic leukaemia -- Malignant lymphomas -- Hodgkin's disease -- Non-Hodgkin's lymphomas -- High-grade -- Low-grade -- Myeloma -- Multiple myeloma -- Clinical features -- Solitary myeloma (plasmacytoma) -- Waldenström's macroglobulinaemia -- Monoclonal gammopathy of undetermined significance -- Amyloidosis -- Investigations of haematological malignancies -- Erythrocyte sedimentation rate and plasma viscosity -- Bone marrow investigation -- Bone marrow smear -- Collection of bone marrow -- Lymph node biopsy -- Cytogenetic analysis -- Chapter 6: Haemostasis -- Platelets and blood coagulation -- Platelet structure and production -- Platelet functions -- Adhesion -- Release reaction -- Platelet aggregation -- Procoagulant function -- Tissue repair -- Antiplatelet drugs -- Platelet disorders -- Reduced platelet count (thrombocytopenia) -- Decreased platelet production -- Generalized disease of the bone marrow -- Specific impairment of platelet production -- Ineffective megakaryopoiesis -- Decreased platelet survival -- Immune destruction -- Thrombotic thrombocytopenic purpura (TTP) and haemolytic-uraemic syndrome (HUS) -- Dilutional thrombocytopenia -- Splenic sequestration -- Defects of platelet function -- The coagulation cascade -- The coagulation pathways -- The extrinsic pathway -- The intrinsic pathway -- Fibrin -- Initiation and propagation -- Regulatory pathways -- Proteins C and S -- Antithrombin -- Role of vitamin K -- Role of calcium -- Fibrinolysis -- Tissue plasminogen activator -- Plasmin -- Clotting tests
  • Overview of haemostasis -- Clotting factor disorders -- Hereditary factor abnormalities -- von Willebrand's disease -- Haemophilia A -- Factor replacement therapy -- Haemophilia B -- Other deficiencies -- Acquired factor abnormalities -- Vitamin K deficiency -- Liver disease -- Disseminated intravascular coagulation -- Thrombosis -- Changes in blood flow -- Changes within the walls of blood vessels -- Changes in blood constituents (hypercoagulability) -- Primary (hereditary) thrombophilia -- Activated protein C resistance due to factor V Leiden -- Antithrombin deficiency -- Deficiencies of proteins C and S -- Defective fibrinolysis -- Prothrombin allele G20210A -- Hyperhomocysteinaemia -- Secondary (acquired) thrombophilia -- Anticoagulation -- Warfarin -- Heparin -- Thromboprophylaxis -- Therapeutic fibrinolysis -- Chapter 7: Blood transfusion -- Introduction in blood products -- Indications for red cell transfusion -- Red-cell antigens -- ABO antigens -- Rhesus antigens -- RhD haemolytic disease of the newborn -- Prevention of RhD haemolytic disease of the newborn -- Other red-cell antigens -- Cross-matching and blood transfusion -- Cross-matching blood -- Emergency transfusions -- Filtering and warming at transfusion -- Dangers in the use of blood products -- Transfusion reaction -- Haemolytic transfusion reactions -- Blood products and infection risk -- Iron overload -- Other blood products -- Platelets -- Fresh-frozen plasma -- Cryoprecipitate -- Clotting factor concentrates -- White cells -- Chapter 8: Principles of immunology -- An overview of immunology -- Overview of the innate immune system -- Overview of the adaptive immune system -- Cytokines -- Chapter 9: The innate immune system -- Barriers to infection -- Physical and mechanical -- Chemical -- Biological (normal flora) -- Cells of innate immunity -- Phagocytes
  • Neutrophils (for structure, see p. 37 -- for production, see p. 2) -- Mononuclear phagocyte system -- Killing by phagocytes -- Natural killer (NK) cells -- Mast cells and basophils (for structure, see p. 40) -- Eosinophils (for structure, see p. 38) -- Soluble proteins -- Acute phase proteins -- C-reactive protein -- Serum amyloid A -- Erythrocyte sedimentation rate -- The complement system -- The classical pathway -- The alternative pathway -- The lectin pathway -- C3 convertase -- Effectors of complement -- Inhibitors of complement -- Innate immune system pattern recognition molecules -- Chapter 10: The adaptive immune system -- The immunoglobulin domain -- Structure of B and T cell surface antigen receptors -- Structure of immunoglobulin -- The major histocompatibility complex (MHC) -- The MHC genes -- Structure and function of the MHC -- MHC restriction -- Antigen processing and presentation -- Structure and function of CD4 and CD8 -- Generation of antigen receptor diversity -- Genetic rearrangements -- Junctional diversity -- Junctional flexibility and N-nucleotide addition -- Somatic hypermutation -- Class switching -- Humoral immunity -- B cells and antibody production -- Structure and function of antibody -- The light chain -- The heavy chain -- The variable domain -- The hinge region -- Classes of antibody -- The functions of antibodies -- Lymphatic drainage and lymph nodes -- Lymphatic circulation -- Lymph nodes -- Lymphocyte recirculation -- Lymphadenopathy -- Mucosal-associated lymphoid tissue (MALT) -- Organized lymphoid tissue -- Respiratory tract -- Gastrointestinal tract -- Lymphocyte trafficking in MALT -- Cell-mediated immunity -- The thymus gland -- Embryological origin of the thymus -- Thymic hypoplasia -- T lymphocytes -- Functions of different T cell phenotypes -- T helper cells -- Cytotoxic T cells -- Development of T cells
  • Positive selection
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unknown
http://library.link/vocab/discovery_link
{'f': 'http://opac.lib.rpi.edu/record=b3787898'}
Edition
4th ed.
Extent
1 online resource (193 pages)
Form of item
online
Isbn
9780723438922
Media category
computer
Media MARC source
rdamedia
Media type code
c
Sound
unknown sound
Specific material designation
remote

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