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The Resource Computational Methods for Processing and Analysis of Biological Pathways

Computational Methods for Processing and Analysis of Biological Pathways

Label
Computational Methods for Processing and Analysis of Biological Pathways
Title
Computational Methods for Processing and Analysis of Biological Pathways
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Contributor
Subject
Language
eng
Member of
Cataloging source
MiAaPQ
Literary form
non fiction
Nature of contents
dictionaries
Series statement
SpringerBriefs in Computer Science
Computational Methods for Processing and Analysis of Biological Pathways
Label
Computational Methods for Processing and Analysis of Biological Pathways
Link
http://libproxy.rpi.edu/login?url=https://ebookcentral.proquest.com/lib/rpi/detail.action?docID=4821978
Publication
Copyright
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Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
  • Preface -- Contents -- 1 Introduction -- Abstract -- 1.1 Biological Networks -- 1.1.1 Properties -- 1.1.2 Categories of Biological Networks -- 1.2 Pathway Analysis -- 1.2.1 Methodology -- 1.2.2 Evolution of Pathway Analysis Methods -- 1.3 Systems Pharmacology -- References -- 2 Networks and Pathways in Systems Pharmacology -- Abstract -- 2.1 Introduction -- 2.2 Network- and Pathway/Sub-pathway-Based Characterization of Drugs Mechanism of Action -- 2.3 Identification of New Drug Targets and Polypharmacology Applications -- 2.3.1 Target Characterization and Identification Using Network Properties of Drug Targets -- 2.3.2 Identification of Drug Targets Based on Integrative Network Approaches -- 2.3.3 Network-Based Polypharmacology -- 2.4 Network-Based Drug Repositioning -- 2.4.1 Drug Repositioning Based on Molecular Profiles -- 2.4.2 Drug Repositioning Based on Phenotypic Profiles -- 2.5 Network-Based Side Effect Modeling and Prediction -- 2.5.1 Approaches Based on Chemical Structure -- 2.5.2 Approaches Based on Pathways/Sub-pathways -- 2.6 Current Challenges and Future Considerations -- References -- 3 Time-Varying Methods for Pathway and Sub-pathway Analysis -- Abstract -- 3.1 Introduction -- 3.2 Conversion of Pathway Databases to Graphs -- 3.3 Time-Varying Pathway and Sub-pathway Extraction -- 3.3.1 Linear Sub-pathway Extraction -- 3.3.2 Nonlinear Sub-pathway Extraction -- 3.4 Temporal Dynamics Scoring Schemes -- 3.4.1 Approach Followed in CHRONOS -- 3.4.2 Other Approaches -- 3.5 Synthetic and Biological Data Analysis Results -- References -- 4 Identification of Differentially Expressed Pathways and Sub-pathways -- Abstract -- 4.1 Introduction -- 4.2 Approaches Based on Gene Sets -- 4.3 Approaches Based on Pathway Topology -- 4.4 Conversion of Pathway Databases Information to Graphs
  • 4.5 Gene and Pathway-Level Statistics of Differential Expression -- 4.5.1 Methods Using Experimental Data for Sub-pathway Identification -- 4.5.2 Methods Using Experimental Data for Evaluating the Statistical Significance of Sub-pathways -- 4.6 DEsubs: A Flexible Tool for Identification of Differentially Expressed Sub-pathways -- References
http://library.link/vocab/cover_art
https://contentcafe2.btol.com/ContentCafe/Jacket.aspx?Return=1&Type=S&Value=9783319538686&userID=ebsco-test&password=ebsco-test
Dimensions
unknown
http://library.link/vocab/discovery_link
{'f': 'http://opac.lib.rpi.edu/record=b4387656'}
Extent
1 online resource (96 pages)
Form of item
online
Isbn
9783319538686
Media category
computer
Media MARC source
rdamedia
Media type code
c
Sound
unknown sound
Specific material designation
remote

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