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The Resource Combinatorial peptide library protocols, edited by Shmuel Cabilly

Combinatorial peptide library protocols, edited by Shmuel Cabilly

Label
Combinatorial peptide library protocols
Title
Combinatorial peptide library protocols
Statement of responsibility
edited by Shmuel Cabilly
Contributor
Subject
Language
eng
Summary
Shmuel Cabilly presents in Combinatorial Peptide Library Protocols a collection of new and unique techniques for the construction and use of peptide libraries. These powerful methods-often detailed here by their pioneers-include protocols for the chemical synthesis of peptide libraries, for constructing peptide libraries that are displayed on the surface of filamentous phage or bacteria, and for the rapid screening of these libraries for molecules with biospecific properties. Additional methods permit identifying specific enzyme substrates, investigating the recognition spectra of various binding proteins, epitope mapping, and identifying mimotopes. Combinatorial Peptide Library Protocols offers novice and experienced investigators alike the ability to select molecules from a randomized pool having specific biological activities. Its state-of-the-art techniques, combined with clear step-by-step instructions, make this book an essential tool in the selection of peptides suitable for drug development
Member of
Cataloging source
YNG
Illustrations
illustrations
Index
index present
Language note
English
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Series statement
Methods in molecular biology
Series volume
v. 87
Target audience
adult
Combinatorial peptide library protocols, edited by Shmuel Cabilly
Label
Combinatorial peptide library protocols, edited by Shmuel Cabilly
Link
http://libproxy.rpi.edu/login?url=http://link.springer.com/10.1385/0896033929
Publication
Related Contributor
Related Location
Related Agents
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Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Synthesis of a one-bead one-compound combinatorial peptide library / Kit S. Lam, Michal Lebl -- Enzyme-linked calorimetric screening of a one-bead one-compound combinatorial library / Kit S. Lam -- Synthesis and screening of positional scanning combinatorial libraries / Colette T. Dooley, Richard A. Houghten -- Synthesis and screening of peptide libraries on continuous cellulose membrane supports / Achim Kramer, Jens Schneider-Mergener -- Peralkylation : "libraries from libraries" : chemical transformation of synthetic combinatorial libraries / John M. Ostresh, Barbara Dörner, Richard A. Houghten -- Introduction to combinatorial solid-phase assays for enzyme activity and inhibition / Morten Meldal -- Preparation of biocompatible resins for library syntheses / Morten Meldal -- Intramolecular fluorescence-quenched substrate libraries / Morten Meldal -- The solid-phase enzyme inhibitor library assay / Morten Meldal -- Determination of peptide substrate motifs for protein kinases using a "one-bead one-compound" combinatorial library approach / Kit S. Lam -- The use of peptide library for the determination of kinase peptide substrates / Zhou Songyang, Lewis C. Cantley -- Analysis of protein kinase substrate specificity by the use of peptide libraries on cellulose paper (SPOT-Method) / Werner J. Tegge, Ronald Frank -- Generation of multiuse peptide libraries for functional screenings / Channa K. Jayawickreme, Shiranthi P. Jayawickreme, Michael R. Lerner -- Functional screening of multiuse peptide libraries using melanophore bioassay / Channa K. Jayawickreme, Shiranthi P. Jayawickreme, Michael R. Lerner -- The basic structure of filamentous phage and its use in the display of combinatorial peptide libraries / Shmuel Cabilly -- Construction and use of a 20-mer phage display epitope library / Baruch Stern, Jonathan M. Gershoni -- Construction of disulfide-constrained random peptide libraries displayed on phage coat protein VIII / Alessandra Luzzago, Franco Felici -- Conformational mimicry through random constraints plus affinity selection / Guangming Zhong -- The use of combinatorial libraries to identify ligands that interact with surface receptors in living cells / Shmuel Cabilly, Judith Heldman, Eliahu Heldman, Ephraim Katchalski-Katzir -- Screening phage display peptide libraries on nitrocellulose membranes / Shmuel Cabilly, Judith Heidman, Ephraim Katchalski-Katzir -- Identification of disease-specific epitopes / Antonella Folgori, Alessandra Luzzago, Paolo Monaci, Alfredo Nicosia, Riccardo Cortese, Franco Felici -- Identification of peptide ligands for the antigen binding receptor expressed on human B-cell lymphomas / Markus F. Renschler, William J. Dower, Ronald Levy -- Major histocompatibility complex allele-specific peptide libraries and identification of T-cell mimotopes / Marc A. Gavin, Michael J. Bevan -- Phage display of peptide libraries on protein scaffolds / Henry B. Lowman -- Displaying libraries of conformationally constrained peptides on the surface of Escherichia coli as flagellin fusions / Zhijan Lu, Brian C. Tripp, John M. McCoy -- Combinatorial peptide library as an immunogen / J. Estaquier, J.-C. Ameisen, C. Auriault, C. Boutillon, H. Gras-Masse, A. Tartar
http://library.link/vocab/cover_art
https://contentcafe2.btol.com/ContentCafe/Jacket.aspx?Return=1&Type=S&Value=9781592595716&userID=ebsco-test&password=ebsco-test
Dimensions
unknown
http://library.link/vocab/discovery_link
{'f': 'http://opac.lib.rpi.edu/record=b3357162'}
Extent
1 online resource (xiii, 313 pages)
File format
one file format
Form of item
online
Isbn
9781592595716
Lccn
97036646
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations (some color).
Quality assurance targets
unknown
Reformatting quality
access
Specific material designation
remote

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