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The Resource Chromosome Structure and Aberrations

Chromosome Structure and Aberrations

Label
Chromosome Structure and Aberrations
Title
Chromosome Structure and Aberrations
Creator
Contributor
Subject
Language
eng
Cataloging source
MiAaPQ
Literary form
non fiction
Nature of contents
dictionaries
Chromosome Structure and Aberrations
Label
Chromosome Structure and Aberrations
Link
http://libproxy.rpi.edu/login?url=https://ebookcentral.proquest.com/lib/rpi/detail.action?docID=4803139
Publication
Copyright
Related Contributor
Related Location
Related Agents
Related Authorities
Related Subjects
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
  • Dedication -- Foreword -- Preface -- Contents -- Contributors -- About the Editors -- 1: Introduction to Chromosome -- 1.1 Introductory Remarks -- 1.2 Early History of Chromosome -- 1.3 Chemical Nature of Chromosome -- 1.4 Chromosome Packaging -- 1.5 Chromosomal Aberrations -- 1.6 Artificial Chromosomes -- 1.7 Chromosome Painting -- Glossary -- References and Additional Reading -- 2: B Chromosomes -- 2.1 Introduction -- 2.2 B Chromosome Inheritance Mechanisms -- 2.3 Origins and Sequence Content of B Chromosomes -- 2.4 What Are B Chromosomes Doing? -- 2.5 Applications for B Chromosomes -- 2.6 Conclusions -- Glossary -- References -- 3: Organization of Genetic Material into Chromosomes -- 3.1 Chromatin -- 3.2 Structure of a Metaphase Chromosome -- 3.2.1 Chromatids -- 3.2.2 Chromomeres -- 3.2.3 Centromeres (CEN Region) -- 3.2.4 Secondary Constriction -- 3.2.5 Telomeres -- 3.3 Molecular Structure of Chromosomes -- 3.3.1 Histones -- 3.3.2 Nonhistone Chromosomal Proteins -- 3.3.3 DNA Structure -- 3.3.3.1 Brief History -- 3.3.3.2 Evidence that DNA Is the Genetic Material -- 3.3.3.3 Structure of DNA and RNA -- 3.3.3.4 Double Helical Structure of DNA -- 3.4 Chromosome Structure in Prokaryotes -- 3.5 Chromosomal Structure in Eukaryotes -- 3.5.1 Structure of Metaphase Chromosome After Histone Depletion -- 3.5.2 Laemmli's Radial Loop Model of Chromosome Without Histone Depletion -- Glossary -- References and Additional Reading -- 4: Laboratory Techniques of Studying Plant Chromosomes -- 4.1 Introduction -- 4.2 Pretreatment -- 4.2.1 Colchicine -- 4.2.2 Ü-Bromonaphthalene -- 4.2.3 Ice Cold Water -- 4.2.4 8-Hydroxyquinoline -- 4.2.5 p-Dichlorobenzene (p-DCB) -- 4.3 Fixation -- 4.3.1 Mercuric Chloride (HgCl2) -- 4.3.2 Potassium Dichromate (K2Cr2O7) -- 4.3.3 Chromic Acid (H2CrO4) or Chromium Trioxide (CrO3)
  • 4.3.4 Osmium Tetroxide (OsO4) -- 4.3.5 Ethanol (C2H5OH) -- 4.3.6 Acetic Acid (CH3COOH) -- 4.3.7 Formaldehyde (HCHO) -- 4.3.8 Propionic Acid (C2H5COOH) -- 4.3.9 Chloroform (CHCl3) -- 4.4 Fixing Mixtures -- 4.4.1 Flemming's Weak Fluid (1882) and Flemming's Strong Fluid (1884) -- 4.4.2 Carnoy's Fluid (1886) -- 4.4.3 Carnoy's Fluid II (1886) -- 4.4.4 Navaschin's Fluid (Navaschin 1925) -- 4.5 Stain and Staining -- 4.5.1 Carmine -- 4.5.2 Orcein -- 4.5.3 Crystal Violet (Methyl Violet 10B) -- 4.5.4 Hematoxylin -- 4.5.5 Fuchsine (Fuschin) -- 4.5.5.1 The Feulgen Reaction -- 4.6 Preparations of Some of the Important Stains Used in Squash and Smear Techniques -- 4.6.1 Acetocarmine, Aceto-orcein -- 4.6.2 Crystal Violet -- 4.6.3 Schiff's Reagent/Fuchsine Reagent -- 4.7 Squash and Smear Preparation -- 4.7.1 Smear Method -- 4.7.2 Squash Method -- 4.7.3 Making Slides Permanent -- References -- 5: Flow Cytometry and Its Utility -- 5.1 Introduction -- 5.2 Flow Cytometric Measurement -- 5.2.1 Absorbance and Scattering Monitoring -- 5.2.2 Fluorescence Monitoring -- 5.2.3 Probes -- 5.3 Utility of Flow Cytometry -- 5.3.1 Cell Size, Shape, and Granularity -- 5.3.2 Viability and Apoptosis -- 5.3.3 Nuclear DNA Content, Cell Cycle, and Ploidy -- 5.3.4 Flow Karyotyping and Chromosome Sorting -- 5.3.4.1 Chromosome Aberrations -- 5.3.4.2 Physical Mapping -- 5.3.4.3 Genetic Marker Development -- 5.3.4.4 Sequencing and Chromosome Genomics -- 5.3.4.5 Chromosome Proteomics -- 5.3.5 Immunophenotyping and Clinical Uses -- 5.4 Limitations and Future Prospects -- Glossary -- References -- 6: Asynapsis and Desynapsis in Plants -- 6.1 Introduction -- 6.2 Synaptic Mutations -- 6.3 Asynapsis and Desynapsis -- 6.4 Cytological Consequences of Asynapsis and Desynapsis -- 6.5 2n Gamete Formation and Role in Polyploidy
  • 6.6 Practical Applications of Asynapsis and Desynapsis -- References -- 7: Cytogenetic Studies in Indian Drimia Jacq. (Urgineoideae: Hyacinthaceae) -- 7.1 Taxonomy -- 7.1.1 Present Status -- 7.1.2 Nomenclature -- 7.2 Life Cycle Pattern, Reproductive Isolation and Phenology -- 7.3 Hybridization and Breeding System -- 7.4 Cytogenetics -- 7.4.1 Base Number -- 7.4.2 Cytotypes -- 7.4.3 B Chromosomes -- 7.4.4 Karyotype Diversity and Evolution -- References -- 8: Banding Techniques in Chromosome Analysis -- 8.1 Introduction -- 8.2 Chromosome Banding Techniques and Mechanisms -- 8.2.1 Q-Banding -- 8.2.1.1 Protocol: Barch et al. (1991) -- 8.2.1.2 Preparations -- 8.2.1.3 Procedure -- 8.2.2 G-Banding -- 8.2.2.1 Protocol: Barch et al. (1991) -- 8.2.2.2 Preparations -- 8.2.2.3 Procedure -- 8.2.3 C-Banding -- 8.2.3.1 Protocol: Friebe and Gill (1994) -- 8.2.3.2 Preparations -- 8.2.3.3 Procedure -- 8.2.4 R-Banding -- 8.2.4.1 Protocol: Verma and Babu (1989) -- 8.2.4.2 Preparations -- 8.2.4.3 Procedure -- 8.2.5 N-Banding -- 8.2.5.1 Protocol: Gill et al. (1991) -- 8.2.5.2 Preparations -- 8.2.5.3 Procedure -- References -- 9: Karyotype Evolution: Concepts and Applications -- 9.1 Introduction -- 9.2 Evolutionary Aspects of Chromosome Polymorphisms -- 9.3 Description and Procedure for Obtaining the Karyotype -- 9.4 Applications of Karyotype Analysis -- Glossary -- References -- 10: Polyploidy: Evolution and Crop Improvement -- 10.1 Introduction -- 10.2 Changes in Chromosome Number -- 10.3 Origin of Polyploidy -- 10.3.1 Origin of Autopolyploidy -- 10.3.2 Origin of Allopolyploidy -- 10.4 Methods for Inducing Polyploidy -- 10.5 Role of Polyploidy in Plant Evolution -- 10.5.1 Autopolyploidy and Evolution -- 10.5.2 Allopolyploidy and Evolution -- 10.6 Polyploidy and Crop Improvement -- 10.7 Conclusions -- References -- Links
  • 11: Mutagenic Effects on Meiosis in Legumes and a Practical Case Study of Vicia faba L. -- 11.1 Description of Vicia faba L. -- 11.1.1 Origin -- 11.1.2 Taxonomy, Morphology and Floral Biology -- 11.1.3 Ecology -- 11.1.4 Yield and Economics -- 11.1.5 Uses -- 11.2 Cytology -- 11.2.1 Cytological Analysis -- 11.2.2 Cytological Observations in M1 Generation -- 11.2.2.1 Univalents -- 11.2.2.2 Multivalents -- 11.2.2.3 Stickiness -- 11.2.3 Precocious Movement -- 11.2.4 Stray Chromosomes -- 11.2.5 Non-orientation -- 11.2.6 Fragments -- 11.3 Chromosomal Aberrations at Anaphase I and II -- 11.3.1 Laggards -- 11.3.2 Bridges -- 11.3.3 Unequal Separation -- 11.3.4 Disturbed Polarity -- 11.3.5 Cytomixis -- 11.4 Chromosomal Aberrations at Telophase I and II -- 11.4.1 Micronuclei -- 11.4.2 Multinucleate Condition -- 11.4.3 Non-disjunction -- 11.5 Chiasma Frequency -- 11.6 Effect of Mutagens on Biological Parameters -- References -- 12: Structural Changes in Chromosomes -- 12.1 Changes in Chromosome Structure -- 12.1.1 Deletions (Deficiencies) -- 12.1.1.1 Terminal Deletion -- 12.1.1.2 Interstitial Deletions -- 12.1.2 Duplications -- 12.1.3 Inversions -- 12.1.4 Translocation -- 12.1.4.1 Reciprocal Translocation -- 12.1.4.2 Robertsonian Translocation -- 12.1.4.3 Translocations and Tumors -- Glossary -- References and Additional Reading -- 13: Numerical Changes in Chromosomes -- 13.1 Chromosome Number -- 13.2 Abnormal Chromosomal Number/Aneuploidy -- 13.2.1 Monoploidy -- 13.2.2 Polyploids -- 13.2.2.1 Polyploidy in Plants -- 13.2.2.2 Polyploidy in Animals -- 13.2.3 Aneuploidy in Humans -- 13.2.3.1 Trisomy (2n + 1) -- 13.2.3.1.1 Trisomy in Autosomes -- Trisomy 21 (Down Syndrome) -- Trisomy 18 (47, +18 -- Edwards Syndrome) -- Trisomy 13 (47, +13) -- Trisomy 8 -- 13.2.3.1.2 Trisomies in Sex Chromosomes -- Sex Chromosome Trisomies in Males
  • 13.2.4 Nullisomy (2n{u2212}2) -- 13.2.5 Monosomy (2n{u2212}1) (XO or Turner Syndrome) -- Glossary -- References and Additional Reading -- 14: Techniques of Chromosomal Studies -- 14.1 Introduction -- 14.2 Karyotyping -- 14.2.1 Chromosome Banding -- 14.2.2 Visible Light Chromosome Staining -- 14.2.3 Fluorescent Chromosome Staining -- 14.2.4 Heavy Metal Staining -- 14.3 Genetic Mapping -- 14.3.1 Linkage and Recombination-Based Maps -- 14.3.2 Marker-Based Maps -- 14.4 Fluorescence In Situ Hybridization -- 14.5 Multiplex FISH -- 14.6 Spectral Karyotyping -- 14.7 Flow Cytogenetics -- 14.8 Microarray -- 14.9 Microarray Technique -- 14.10 Comparative Genomic Hybridization (CGH) Array -- 14.11 Tiling Arrays -- 14.12 Single-Nucleotide Polymorphism (SNP) Arrays -- 14.13 Next-Generation Sequencing -- 14.14 Whole Genome Sequencing -- 14.15 Whole Exome Sequencing -- 14.16 Targeted Sequencing -- Glossary -- References -- 15: Cytomixis: Causes and Consequences as a Case Study in Vicia faba L. -- 15.1 Description of Vicia faba L. -- 15.1.1 Origin -- 15.1.2 Taxonomy, Morphology, and Floral Biology -- 15.1.3 Ecology -- 15.1.4 Yield and Economics -- 15.1.5 Uses -- 15.2 Cytology -- 15.2.1 Cytological Aberrations -- 15.2.2 Cytomixis -- 15.2.3 Origin of Cytomixis -- 15.2.4 Factors Affecting Cytomixis -- 15.2.5 Frequency and Intensity of Cytomixis -- 15.2.6 Consequences of Cytomixis -- 15.2.7 Comparative Mutagenicity and Cytomixis -- 15.2.8 Conclusions -- References -- 16: Fluorescence In Situ Hybridization (FISH) and Its Applications -- 16.1 Introduction -- 16.2 Advancement in Fish Techniques -- 16.3 Principle Involved in Fish -- 16.4 Preparation of Probes -- 16.5 Methodology Involved -- 16.5.1 Cytological Preparation -- 16.5.2 Probe Labeling -- 16.5.3 In Situ Hybridization -- 16.5.3.1 Nonradioactive In Situ Hybridization
  • 16.5.3.2 Genomic In Situ Hybridization (GISH)
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1 online resource (377 pages)
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online
Isbn
9788132236733
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computer
Media MARC source
rdamedia
Media type code
c
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