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The Resource Chemogenomics : methods and applications, edited by Edgar Jacoby

Chemogenomics : methods and applications, edited by Edgar Jacoby

Label
Chemogenomics : methods and applications
Title
Chemogenomics
Title remainder
methods and applications
Statement of responsibility
edited by Edgar Jacoby
Contributor
Subject
Genre
Language
eng
Summary
The establishment, analysis, prediction, and expansion of a comprehensive ligand-target Structure-Activity Relationship (SAR) in the post-genomic era presents a key research challenge for this century. In Chemogenomics: Methods and Applications, experts from academia and industry explore cutting-edge in vitro and in silico approaches available today and outline the relevant aspects of chemistry, biology, and molecular informatics which are the cornerstones of chemogenomics, thus combining introductory concepts with detailed methods and protocols. Covering topics such as target family-oriented compound library design, drug discovery targeting the purinome and co-factor binding sites, as well as the pocketome engine and molecular interaction field approaches, the book emphasizes systemization as an advantage to furthering the difficult science of drug discovery. As a volume in the highly successful Methods in Molecular Biology series format, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and practical, Chemogenomics: Methods and Applications presents content which will be of enormous value to those striving for the discovery of new and better therapies for diseases
Member of
Cataloging source
CUS
Illustrations
illustrations
Index
index present
Language note
English
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Series statement
  • Springer protocols
  • Methods in molecular biology,
Series volume
575
Chemogenomics : methods and applications, edited by Edgar Jacoby
Label
Chemogenomics : methods and applications, edited by Edgar Jacoby
Link
http://libproxy.rpi.edu/login?url=http://link.springer.com/10.1007/978-1-60761-274-2
Publication
Related Contributor
Related Location
Related Agents
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Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Organizing bioactive compound discovery in target families / H. Peter Nestler -- Compound library design for target families / K.V. Balakin, Y.A. Ivanenkov, and N.P. Savchuk -- Targeting the purinome / Jeremy M. Murray and Dirksen E. Bussiere -- Cofactor chemogenomics / Ratna Singh and Andrea Mozzarelli -- Chemogenomics with protein secondary-structure mimetics / Garland R. Marshall, Daniel J. Kuster, and Ye Che -- Database systems for knowledge-based discovery / Sarma A.R.P. Jagarlapudi and K.V. Radha Kishan -- Knowledge-based virtual screening : application to the MDM4/p53 protein-protein interaction / Edgar Jacoby [and others] -- Off-target networks derived from ligand set similarity / Michael J. Keiser and Jérôme Hert -- Chemogenomic analysis of safety profiling data / Josef Scheiber and Jeremy L. Jenkins -- Network and pathway analysis of compound-protein interactions / Richard J. Brennan, Tatiana Nikolskya, and Svetlana Bureeva -- The flexible pocketome engine for structural chemogenomics / Ruben Abagyan and Irina Kufareva -- Structure-based chemogenomics : analysis of protein family landscapes / Bernard Pirard -- Hypothesis-driven screening / Ulrich Schopfer [and others]
http://library.link/vocab/cover_art
https://contentcafe2.btol.com/ContentCafe/Jacket.aspx?Return=1&Type=S&Value=9781607612742&userID=ebsco-test&password=ebsco-test
Dimensions
unknown
http://library.link/vocab/discovery_link
{'f': 'http://opac.lib.rpi.edu/record=b3357397'}
Extent
1 online resource (x, 320 pages)
Form of item
online
Isbn
9781607612742
Lccn
2009932720
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations (some color).
Reproduction note
Electronic reproduction.
Sound
unknown sound
Specific material designation
remote
System details
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.

Library Locations

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