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The Resource Chemical genomics and proteomics : reviews and protocols, edited by Edward D. Zanders

Chemical genomics and proteomics : reviews and protocols, edited by Edward D. Zanders

Contributor
Summary
Chemical genomics technology has been steadily improving, delivering new biological probes and drugs, and the explicit use of the term 'chemical proteomics' has increased with it, as proteins have always been at the heart of this technology. In Chemical Genomics and Proteomics: Reviews and Protocols, experts in the field present updated reviews of the chemistry of small molecules and their interaction with protein targets as well as detailed protocols that cover different types of ligands, carbohydrates, and lipids. For example, the generation of their protein targets and methods for measuring their interactions is covered. Written in the highly successful Methods in Molecular Biology"!series format, methodology chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and up to date, Chemical Genomics and Proteomics: Reviews and Protocols aims to provide inspiration to those who wish to use chemical genomics and proteomics in their work and develop this young field into full maturity through the incorporation of the new biological and chemical technologies beginning to emerge here
Language
eng
Work
Publication
Extent
1 online resource (xi, 243 pages)
Contents
  • Overview of chemical genomics and proteomics
  • Exploring chemical space: Recent advances in chemistry
  • In silico design of small molecules
  • Surface plasmon resonance for proteomics
  • Biomimetic affinity ligands for immunoglobulins based on the multicomponent ugi reaction
  • Preparation of photo-cross-linked small molecule affinity matrices for affinity selection of protein targets for biologically active small molecules
  • Profiling cellular myristoylation and palmitoylation using [omega]-alkynyl fatty acids
  • Fluorescence labels in kinases: A high-throughput kinase binding assay for the identification of DFG-out binding ligands
  • Electrochemical aptamer sensor for small molecule assays
  • Miniaturized, microarray-based assays for chemical proteomic studies of protein function
  • Glycan microarrays
  • Resolving bottlenecks for recombinant protein expression in E. coli
  • Recombinant protein expression in the baculovirus-infected insect cell system
  • Systems for the cell-free synthesis of proteins
  • Protein identification by MALDI-TOF mass spectrometry
Isbn
9781617793493
Link
http://libproxy.rpi.edu/login?url=http://link.springer.com/10.1007/978-1-61779-349-3
Instance
Label
Chemical genomics and proteomics : reviews and protocols
Title
Chemical genomics and proteomics
Title remainder
reviews and protocols
Statement of responsibility
edited by Edward D. Zanders
Contributor
Subject
Genre
Language
eng
Summary
Chemical genomics technology has been steadily improving, delivering new biological probes and drugs, and the explicit use of the term 'chemical proteomics' has increased with it, as proteins have always been at the heart of this technology. In Chemical Genomics and Proteomics: Reviews and Protocols, experts in the field present updated reviews of the chemistry of small molecules and their interaction with protein targets as well as detailed protocols that cover different types of ligands, carbohydrates, and lipids. For example, the generation of their protein targets and methods for measuring their interactions is covered. Written in the highly successful Methods in Molecular Biology"!series format, methodology chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and up to date, Chemical Genomics and Proteomics: Reviews and Protocols aims to provide inspiration to those who wish to use chemical genomics and proteomics in their work and develop this young field into full maturity through the incorporation of the new biological and chemical technologies beginning to emerge here
Member of
Cataloging source
SCB
Illustrations
illustrations
Index
index present
Language note
English
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Series statement
Methods in molecular biology,
Series volume
v. 800
Chemical genomics and proteomics : reviews and protocols, edited by Edward D. Zanders
Label
Chemical genomics and proteomics : reviews and protocols, edited by Edward D. Zanders
Link
http://libproxy.rpi.edu/login?url=http://link.springer.com/10.1007/978-1-61779-349-3
Publication
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Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Overview of chemical genomics and proteomics -- Exploring chemical space: Recent advances in chemistry -- In silico design of small molecules -- Surface plasmon resonance for proteomics -- Biomimetic affinity ligands for immunoglobulins based on the multicomponent ugi reaction -- Preparation of photo-cross-linked small molecule affinity matrices for affinity selection of protein targets for biologically active small molecules -- Profiling cellular myristoylation and palmitoylation using [omega]-alkynyl fatty acids -- Fluorescence labels in kinases: A high-throughput kinase binding assay for the identification of DFG-out binding ligands -- Electrochemical aptamer sensor for small molecule assays -- Miniaturized, microarray-based assays for chemical proteomic studies of protein function -- Glycan microarrays -- Resolving bottlenecks for recombinant protein expression in E. coli -- Recombinant protein expression in the baculovirus-infected insect cell system -- Systems for the cell-free synthesis of proteins -- Protein identification by MALDI-TOF mass spectrometry
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https://contentcafe2.btol.com/ContentCafe/Jacket.aspx?Return=1&Type=S&Value=9781617793493&userID=ebsco-test&password=ebsco-test
Dimensions
unknown
http://library.link/vocab/discovery_link
{'f': 'http://opac.lib.rpi.edu/record=b3357667'}
Extent
1 online resource (xi, 243 pages)
Form of item
online
Isbn
9781617793493
Lccn
2011937229
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations.
Specific material designation
remote

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