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The Resource Characterization of nanoparticles intended for drug delivery, edited by Scott E. McNeil

Characterization of nanoparticles intended for drug delivery, edited by Scott E. McNeil

Label
Characterization of nanoparticles intended for drug delivery
Title
Characterization of nanoparticles intended for drug delivery
Statement of responsibility
edited by Scott E. McNeil
Contributor
Subject
Language
eng
Summary
In recent years, there have been many exciting breakthroughs in the application of nanotechnology to medicine. In Characterization of Nanoparticles Intended for Drug Delivery, expert researchers explore the latest advances in the field, providing a set of basic methods for the characterization of nanomaterials for medical use. Chapters provide methods to characterize the physiochemical properties (size, aggregation, and surface chemistry) and in vitro immunological and biological characteristics of nanomaterials. Composed in the highly successful Methods in Molecular Biology series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Comprehensive and informative, Characterization of Nanoparticles Intended for Drug Delivery is an essential survey of methods that are crucial to the preclinical characterization of nanomedicines
Member of
Cataloging source
CUS
Illustrations
illustrations
Index
index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Series statement
  • Springer protocols
  • Methods in molecular biology,
Series volume
697
Characterization of nanoparticles intended for drug delivery, edited by Scott E. McNeil
Label
Characterization of nanoparticles intended for drug delivery, edited by Scott E. McNeil
Link
http://libproxy.rpi.edu/login?url=http://link.springer.com/10.1007/978-1-60327-198-1
Publication
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Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
mixed
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Unique benefits of nanotechnology to drug delivery and diagnostics -- Challenges for nanoparticle characterization -- Considerations when submitting nanotherapeutics to FDA/CDER for regulatory review -- Measuring the hydrodynamic size of nanoparticles in aqueous media using batch-mode dynamic light scattering -- Characterization of nanoparticles by matrix assisted laser desorption ionization time-of-flight mass spectrometry -- Zeta potential measurement -- Size measurement of nanoparticles using atomic force microscopy -- Biological tissue and cell culture specimen preparation for TEM nanoparticle characterization -- SEM x-ray microanalysis of nanoparticles present in tissue or cultured cell thin sections -- Detecting and measuring free gadolinium in nanoparticles for MRI imaging -- Lipid component quantitation by thin layer chromatography -- Detection and quantitative evaluation of endotoxin contamination in nanoparticle formulations by LAL-based assays -- Analysis of microbial contamination in nanoparticle formulations -- Gold nanoparticle quantitation via fluorescence in solution and cell culture -- Quantitation of nanoparticles in serum matrix by capillary electrophoresis -- Evaluation of cytotoxicity of nanoparticulate materials in porcine kidney cells and human hepatocarcinoma cells -- Monitoring nanoparticle-treated hepatocarcinoma cells for apoptosis -- Detecting reactive oxygen species in primary hepatocytes treated with nanoparticles -- Assay to detect lipid peroxidation upon exposure to nanoparticles -- Monitoring glutathione homeostasis in nanoparticle-treated hepatocytes -- Autophagy monitoring assay: Qualitative analysis of MAP LC3-I to II conversion by immunoblot -- Monitoring lysosomal activity in nanoparticle-treated cells -- Method for analysis of nanoparticle hemolytic properties in vitro -- Method for in vitro analysis of nanoparticle thrombogenic properties -- Qualitative analysis of total complement activation by nanoparticles -- Method for analysis of nanoparticle effects on cellular chemotaxis -- In vitro analysis of nanoparticle uptake by macrophages using chemiluminescence
http://library.link/vocab/cover_art
https://contentcafe2.btol.com/ContentCafe/Jacket.aspx?Return=1&Type=S&Value=9781603271981&userID=ebsco-test&password=ebsco-test
Dimensions
unknown
http://library.link/vocab/discovery_link
{'f': 'http://opac.lib.rpi.edu/record=b3357587'}
Extent
1 online resource (xii, 269 pages)
Form of item
online
Isbn
9781603271981
Lccn
2010938916
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations (some color).
Sound
unknown sound
Specific material designation
remote

Library Locations

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      42.729766 -73.682577
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