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The Resource Cellular Osmolytes : From Chaperoning Protein Folding to Clinical Perspectives, edited by Laishram Rajendrakumar Singh, Tanveer Ali Dar, (electronic resource)

Cellular Osmolytes : From Chaperoning Protein Folding to Clinical Perspectives, edited by Laishram Rajendrakumar Singh, Tanveer Ali Dar, (electronic resource)

Label
Cellular Osmolytes : From Chaperoning Protein Folding to Clinical Perspectives
Title
Cellular Osmolytes
Title remainder
From Chaperoning Protein Folding to Clinical Perspectives
Statement of responsibility
edited by Laishram Rajendrakumar Singh, Tanveer Ali Dar
Contributor
Editor
Subject
Language
eng
Summary
This book provides essential insights into improving protein folding/stability, which is a result of the balance between the intra-molecular interactions of protein functional groups and their interactions with the solvent environment. Even a subtle change in the composition of the solvent environment will alter the fidelity of the protein folding process, and hostile environmental stresses represent one of the basic causes of challenges in protein folding or misfolding. Among the strategies employed in a wide range of species and cell types to circumvent the hostile environmental conditions is the elaboration of small organic molecules called osmolytes, and recent advances have revealed that certain specific osmolytes might be key biomarkers of cancer, infectious diseases and are useful in heterologous protein expression and vaccine flocculation. As such a large pool of data has been collected regarding their potential for therapeutic intervention in neurodegenerative diseases and other metabolic disorders caused by protein aggregation or proteiostasis failure
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Literary form
non fiction
Cellular Osmolytes : From Chaperoning Protein Folding to Clinical Perspectives, edited by Laishram Rajendrakumar Singh, Tanveer Ali Dar, (electronic resource)
Label
Cellular Osmolytes : From Chaperoning Protein Folding to Clinical Perspectives, edited by Laishram Rajendrakumar Singh, Tanveer Ali Dar, (electronic resource)
Link
http://libproxy.rpi.edu/login?url=http://dx.doi.org/10.1007/978-981-10-3707-8
Publication
Related Contributor
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Related Agents
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Antecedent source
mixed
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Polyols as exceptional Protein stabilizers -- Osmolyte mixtures versus individuals in protein folding and aggregation -- Molecular insights of Osmolyte-protein Interaction -- MDS simulation studies on osmolyte protein interactions -- Osmolytes as protein aggregation Modifiers -- Osmolytes as Nano-probes of conformational changes -- Inhibition of Protein fibrillation by Chemical chaperones: a Therapeutic strategy -- Osmolyte in Infectious Diseases -- Possible strategies for the therapeutic intervention of osmolyte in Cancer -- Antioxidant osmolytes -- Advances on the in vivo studies of the effect of osmolyte on various pathophysiological conditions -- TMAO in alpha Synuclein aggregation -- Osmolytes: from cell physiology to Disease Prevention -- Osmolytes in Cell-volume Regulation -- Role of Osmolytes in counteracting the deleterious effects of denaturant/pressure
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https://contentcafe2.btol.com/ContentCafe/Jacket.aspx?Return=1&Type=S&Value=9789811037078&userID=ebsco-test&password=ebsco-test
Dimensions
unknown
http://library.link/vocab/discovery_link
{'f': 'http://opac.lib.rpi.edu/record=b4258300'}
Extent
VII, 249 p. 36 illus., 16 illus. in color.
File format
multiple file formats
Form of item
electronic
Isbn
9789811037078
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote

Library Locations

    • Folsom LibraryBorrow it
      110 8th St, Troy, NY, 12180, US
      42.729766 -73.682577
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