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The Resource Cell-based assays for high-throughput screening : methods and protocols, edited by Paul A. Clemons, Nicola J. Tolliday, and Bridget K. Wagner

Cell-based assays for high-throughput screening : methods and protocols, edited by Paul A. Clemons, Nicola J. Tolliday, and Bridget K. Wagner

Label
Cell-based assays for high-throughput screening : methods and protocols
Title
Cell-based assays for high-throughput screening
Title remainder
methods and protocols
Statement of responsibility
edited by Paul A. Clemons, Nicola J. Tolliday, and Bridget K. Wagner
Contributor
Subject
Genre
Language
eng
Summary
As the use of high-throughput screening expands and creates more interest in the academic community, the need for detailed reference materials becomes ever more pressing. Cell-Based Assays for High-Throughput Screening: Methods and Protocols aims to fill an important part of this need by providing an easily accessible reference volume for cell-based phenotypic screening. Leading researchers in the field contribute state-of-the-art methods with actionable protocols covering four major areas of study: model biological systems, screening modalities and assay systems, detection technologies, and approaches to data analysis. Written in the highly successful Methods in Molecular Biology series format, each chapter includes a brief introduction to the subject, lists of necessary materials and reagents, step-by-step laboratory protocols, and a Notes section detailing tips on troubleshooting and avoiding known pitfalls. Cutting-edge and easy-to-use, Cell-Based Assays for High-Throughput Screening: Methods and Protocols presents an overview of relevant approaches, enabling the direct application of existing methods to new discoveries while also inspiring researchers to approach their screening projects in a conceptually modular fashion, enhancing the power to discover through new combinations of existing approaches
Member of
Cataloging source
COO
Illustrations
illustrations
Index
index present
Language note
English
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Series statement
  • Methods in molecular biology,
  • Springer protocols
Series volume
v. 486
Cell-based assays for high-throughput screening : methods and protocols, edited by Paul A. Clemons, Nicola J. Tolliday, and Bridget K. Wagner
Label
Cell-based assays for high-throughput screening : methods and protocols, edited by Paul A. Clemons, Nicola J. Tolliday, and Bridget K. Wagner
Link
http://libproxy.rpi.edu/login?url=http://link.springer.com/10.1007/978-1-60327-545-3
Publication
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Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Introduction: Cell-based assays for high-throughput screening / W.F. An and N.J. Tolliday -- High-throughput screening of model bacteria / S. Zlitni, J.E. Blanchard and E.D. Brown -- Cell-based assays to probe the ERK MAP kinase pathway in endothelial cells / M.R. Wyler [and others] -- Large-scale small-molecule screen using zebrafish embryos / C.C. Hong -- Whole-animal high-throughput screens: The C. elegans model / E.J. O'Rourke, A.L. Conery and T.I. Moy -- Whole-organism screening: Plants / A. Agee and D. Carter -- Fluorescence-based assays / W.F. An -- Reporter gene assays / A.M.F. Liu [and others] -- Screening for chemical inhibitors of heterologous proteins expressed in yeast using a simple growth-restoration assay / A.D. Balgi and M. Roberge -- Assay for isolation of inhibitors of her2-kinase expression / G. Chiosis and A.B. Keeton -- High-content screening: Flow cytometry analysis / B.S. Edwards [and others] -- High-throughput real-time PCR for detection of gene-expression levels / B.K. Wagner and Z. Arany -- Interpretation of uniform-well readouts / S. Josiah -- Extracting rich information from images / A.E. Carpenter
http://library.link/vocab/cover_art
https://contentcafe2.btol.com/ContentCafe/Jacket.aspx?Return=1&Type=S&Value=9781603275453&userID=ebsco-test&password=ebsco-test
Dimensions
unknown
http://library.link/vocab/discovery_link
{'f': 'http://opac.lib.rpi.edu/record=b3681890'}
Extent
1 online resource (x, 218 pages)
Form of item
online
Isbn
9781603275453
Lccn
2008941084
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations.
Specific material designation
remote

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