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The Resource Cancer nanotechnology : methods and protocols, edited by Stephen R. Grobmyer and Brij M. Moudgil

Cancer nanotechnology : methods and protocols, edited by Stephen R. Grobmyer and Brij M. Moudgil

Cancer nanotechnology : methods and protocols
Cancer nanotechnology
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methods and protocols
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edited by Stephen R. Grobmyer and Brij M. Moudgil
Early detection of cancer at the cellular level, even before anatomic anomalies are visible, is critical to more efficacious and cost effective diagnosis and therapeutic advances. In Cancer Nanotechnology: Methods and Protocols, an international panel of experts provide the most recent, cutting-edge, "how-to" approaches developed and employed by researchers in a variety of disciplines to identify cancer specific biomarkers, construct suitable multifunctional targeted nanostructure platforms, along with enhanced imaging and therapeutic applications. Covering such topics as multifunctional and multimodal nanoparticles, nanoparticle mediated cancer theranostics, molecular targets for cancer nanotechnology, and nanoparticles for non-invasive image-guided cancer therapy, the volume addresses the key challenges of the field today, specifically targeted and localized delivery of the drugs. As a volume in the highly successful Methods in Molecular Biology series, the protocols chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cancer Nanotechnology: Methods and Protocols integrates cancer biology, clinical oncology, molecular cancer imaging, materials science and chemical engineering, biomedical engineering, toxicology, computer science, electrical engineering, chemistry, physics, and mathematics in order to achieve the vital goals of nanotechnology-mediated early cancer detection and more efficacious and less toxic therapies for these devastating diseases
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non fiction
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  • dictionaries
  • bibliography
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  • Methods in molecular biology,
  • Springer protocols
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Cancer nanotechnology : methods and protocols, edited by Stephen R. Grobmyer and Brij M. Moudgil
Cancer nanotechnology : methods and protocols, edited by Stephen R. Grobmyer and Brij M. Moudgil
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Includes bibliographical references and index
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online resource
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  • 1. What Is cancer nanotechnology? / Stephen R. Grobmyer, Nobutaka Iwakuma, Parvesh Sharma, and Brij M. Moudgil -- 2. Molecular-targeted therapy for cancer and nanotechnology / Steven N. Hochwald -- 3. Enhanced permeability and retention (EPR) effect for anticancer nanomedicine drug targeting / Khaled Greish -- 4. Nanoparticle characterization for cancer nanotechnology and other biological applications / Scott C. Brown, Maria Palazuelos, Parvesh Sharma, Kevin W. Powers, Stephen M. Roberts, Stephen R. Grobmyer, and Brij M. Moudgil -- 5. Multimodal nanoparticulate bioimaging contrast agents / Parvesh Sharma, Amit Singh, Scott C. Brown, Niclas Bengtsson, Glenn A. Walter, Stephen R. Grobmyer, Nobutaka Iwakuma, Swadeshmukul Santra, Edward W. Scott, and Brij M. Moudgil -- 6. Gold nanocages for cancer imaging and therapy / Leslie Au, Jingyi Chen, Lihong V. Wang, and Younan Xia -- 7. Nanoshells for photothermal cancer therapy / Jennifer G. Morton, Emily S. Day, Naomi J. Halas, and Jennifer L. West -- 8. Gold nanorods: multifunctional agents for cancer imaging and therapy / Alexander Wei, Alexei P. Leonov, and Qingshan Wei -- 9. Polymeric micelles: polyethylene glycol-phosphatidylethanolamine (PEG-PE)-based micelles as an example / Rupa R. Sawant and Vladimir P. Torchilin -- 10. Fluorescent silica nanoparticles for cancer imaging / Swadeshmukul Santra -- 11. Polymeric nanoparticles for drug delivery / Juliana M. Chan, Pedro M. Valencia, Liangfang Zhang, Robert Langer, and Omid C. Farokhzad -- 12. Synthesis, characterization, and functionalization of gold nanoparticles for cancer imaging / Gary A. Craig, Peter J. Allen, and Michael D. Mason -- 13. Identification of pancreatic cancer-specific cell-surface markers for development of targeting ligands / David L. Morse, Galen Hostetter, Yoganand Balagurunathan, Robert J. Gillies, and Haiyong Han
  • 14. Preparation and characterization of doxorubicin liposomes / Guoqin Niu, Brian Cogburn, and Jeffrey Hughes -- 15. PEGylated nanocarriers for systemic delivery / N.K. Jain and Manoj Nahar -- 16. Nanoparticle-aptamer conjugates for cancer cell targeting and detection / M. Carmen Estévez, Yu-Fen Huang, Huaizhi Kang, Meghan B. O'Donoghue, Suwussa Bamrungsap, Jilin Yan, Xiaolan Chen, and Weihong Tan -- 17. Targeting of nanoparticles: folate receptor / Sumith A. Kularatne and Philip S. Low -- 18. Magnetic aerosol targeting of nanoparticles to cancer: nanomagnetosols / Carsten Rudolph, Bernhard Gleich, and Andreas W. Flemmer -- 19. LHRH-targeted nanoparticles for cancer therapeutics / Tamara Minko, Mahesh L. Patil, Min Zhang, Jayant J. Khandare, Maha Saad, Pooja Chandna, and Oleh Taratula -- 20. Antibody targeting of nanoparticles to tumor-specific receptors: immunoliposomes / Miriam Rothdiener, Julia Beuttler, Sylvia K.E. Messerschmidt, and Roland E. Kontermann -- 21. Photoacoustic tomography for imaging nanoparticles / Zhen Yuan and Huabei Jiang -- 22. Current applications of nanotechnology for magnetic resonance imaging of apoptosis / Gustav J. Strijkers, Geralda A.F. van Tilborg, Tessa Geelen, Chris P.M. Reutelingsperger, and Klaas Nicolay -- 23. Applications of gold nanorods for cancer imaging and photothermal therapy / Xiaohua Huang, Ivan H. El-Sayed, and Mostafa A. El-Sayed -- 24. Use of nanoparticles for targeted, noninvasive thermal destruction of malignant cells / Paul Cherukuri and Steven A. Curley -- 25. Colloidal gold: a novel nanoparticle for targeted cancer therapeutics / Anathea C. Powell, Giulio F. Paciotti, and Steven K. Libutti -- 26. Liposomal doxorubicin and nab-paclitaxel: nanoparticle cancer chemotherapy in current clinical use / Alexander Gaitanis and Stephen Staal
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1 online resource (xiii, 396 pages)
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