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The Resource Analysis of Samples of Clinical and Alimentary Interest with Paper-Based Devices

Analysis of Samples of Clinical and Alimentary Interest with Paper-Based Devices

Label
Analysis of Samples of Clinical and Alimentary Interest with Paper-Based Devices
Title
Analysis of Samples of Clinical and Alimentary Interest with Paper-Based Devices
Creator
Subject
Language
eng
Member of
Cataloging source
MiAaPQ
Literary form
non fiction
Nature of contents
dictionaries
Series statement
Springer Theses Ser
Analysis of Samples of Clinical and Alimentary Interest with Paper-Based Devices
Label
Analysis of Samples of Clinical and Alimentary Interest with Paper-Based Devices
Link
http://libproxy.rpi.edu/login?url=https://ebookcentral.proquest.com/lib/rpi/detail.action?docID=4644435
Publication
Copyright
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Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
  • Supervisor's Foreword -- Acknowledgements -- Contents -- Abbreviations -- Introduction -- 1 Paper as a Substrate for Sensors -- 1.1 Composition and Structure -- 1.2 Advantages and Disadvantages of Paper as an Analytical Substrate -- 1.3 Methods of Fabrication -- 1.4 History of Paper in Analytics -- 1.5 Paper-Based Analytics During the Last Decade -- 1.5.1 Enhanced Sensitivity and Signal Amplification -- 1.5.2 Three-Dimensional Architecture -- 1.5.3 Timing and Valving -- 1.5.4 Detection Methods -- 1.5.4.1 Optical Detection -- 1.5.4.2 Equipment Free Optical Detection -- Electrochemical Detection -- References -- 2 Analysis of Glucose, Cholesterol and Uric Acid -- 2.1 Literature Review -- 2.1.1 Importance of Glucose, Cholesterol and Uric Acid -- 2.1.2 Methods of Quantification -- 2.1.2.1 Common Detection Methods -- Glucose -- Uric Acid -- Cholesterol -- 2.1.2.2 Detection on Paper -- Optical -- Electrochemical -- 2.1.3 Quantification of Proteins -- 2.1.3.1 Clinical Significance of Determination of Protein Levels -- 2.1.3.2 Detection of Proteins in Paper-Based Devices -- 2.1.4 Enzyme Immobilization on Paper -- 2.1.5 Flow in Paper Matrix -- 2.1.5.1 Fluid Mechanics in Micro and Nano-Scale -- 2.1.5.2 Flow in Paper Channel -- 2.1.5.3 Computer Modeling -- 2.2 Materials and Methods -- 2.2.1 Reagents and Materials -- 2.2.2 Equipment -- 2.2.3 Substrate -- 2.2.3.1 Types of Paper -- 2.2.3.2 Analysis of Paper Surface -- 2.2.4 Analysis of Glucose, Cholesterol and Uric Acid -- 2.2.4.1 Optical Detection -- Fabrication of Prototype Devices -- Choice of Colorimetric Method -- Differences in Hue and Repeatability of Digitalization -- Solving the Autoxidation Problem -- New Fabrication Methods for Analysis of Cholesterol -- Immobilization of the Colorimetric Reagent for Enhanced Uniformity of Color Development of Uric Acid Assay -- Calibration Curves
  • Tangential Flow Devices -- 2.2.4.2 Methods of Enzyme Immobilization on Paper -- Protein Quantification Methods -- Enzymatic Activity, Optimization of Assay Conditions -- Enzyme Immobilization Methods -- Impact of Enzyme Immobilization on Stability During Storage -- Impact of Enzyme Immobilization on Flow in Paper Channel -- Michaelis-Menten Kinetics -- 2.2.4.3 Electrochemical Detection -- Optimization of Device's Architecture -- Analysis of Glucose and Uric Acid -- Preliminary Tests -- Preliminary Test Destined to Construct a Calibration Curve -- Uniformity of Enzyme Immobilization -- Electrode Positioning -- Calibration Curve -- (Tutaj)Analysis of Glucose, Cholesterol and Uric Acid -- Architecture -- Conservation of Laminar Flow -- Preliminary Tests and Optimization of the Architecture -- 2.3 Results and Discussion -- 2.3.1 Substrate -- 2.3.2 Optical Detection -- 2.3.2.1 Choice of Colorimetric Method -- 2.3.2.2 Differences in Hue and Repeatability of Digitalization -- 2.3.2.3 Solving the Autoxidation Problem -- 2.3.2.4 New Fabrication Methods for Analysis of Cholesterol -- 2.3.2.5 Immobilization of the Colorimetric Reagent for Enhanced Uniformity of Color Development of Uric Acid Assay -- 2.3.2.6 Calibration Curves -- 2.3.2.7 Tangential Flow Devices -- 2.3.3 Methods of Enzyme Immobilization on Paper -- 2.3.3.1 Protein Quantification Methods -- 2.3.3.2 Enzymatic Activity, Optimization of Assay Conditions -- 2.3.3.3 Enzyme Immobilization on Paper-Quantification of Proteins -- 2.3.3.4 Impact of Enzyme Immobilization on Stability During Storage -- 2.3.3.5 Impact of Enzyme Immobilization on Flow in Paper Channel -- 2.3.3.6 Michaelis-Menten Kinetics -- 2.3.4 Electrochemical Detection -- 2.3.4.1 Analysis of Glucose and Uric Acid -- Optimization of Device's Architecture -- Preliminary Test Destined to Construct a Calibration Curve
  • Uniformity of Enzyme Immobilization -- Electrode Positioning -- Calibration Curve -- 2.3.4.2 Analysis of Glucose, Cholesterol and Uric Acid -- Architecture -- Conservation of Laminar Flow -- Preliminary Tests and Optimization of the Architecture -- 2.4 Partial Conclusions -- References -- 3 Electronic Tongue Systems for the Analysis of Beverages -- 3.1 Literature Review -- 3.1.1 Sensor Arrays -- 3.1.2 Analytical Techniques -- 3.1.3 Signal Processing -- 3.1.3.1 Signal Types -- 3.1.3.2 Data Preprocessing and Processing -- 3.1.3.3 Chemometry -- 3.1.4 Potentiometric Sensors for Electronic Tongue Systems -- 3.1.4.1 Working Principle -- 3.1.4.2 Cross-sensitivity -- 3.1.4.3 Types of Ion Selective Electrodes -- Liquid Membrane Electrodes -- Construction of Ion Selective Electrodes -- 3.1.4.4 Paper-Based Potentiometric Sensors -- 3.1.4.5 Detectors -- 3.1.5 Application of Sensor Arrays -- 3.1.5.1 Discrimination of Forged Mineral Water Samples -- 3.1.5.2 Classification of Beverages -- Beer -- Wine -- 3.1.6 Paper-Based Electronic Tongues -- 3.2 Materials and Methods -- 3.2.1 Reagents and Materials -- 3.2.2 Equipment -- 3.2.3 Development of Potentiometric Sensors -- 3.2.3.1 Choice of Electrode Material -- 3.2.3.2 Choice of Insulation -- 3.2.3.3 Type of Paper -- 3.2.3.4 Electrode Architecture -- 3.2.3.5 Optimized Fabrication Procedure -- 3.2.4 Discrimination of Forged Water Samples -- 3.2.4.1 Electrode Matrix for the Discrimination of Forged Water Samples -- 3.2.4.2 Reference Electrode -- 3.2.4.3 Electrode Characterization -- 3.2.4.4 Electronic Tongue -- 3.2.4.5 Water Samples -- 3.2.4.6 Chemometric Analysis -- 3.2.5 Integration of Reference Electrode -- 3.2.5.1 Preparation of Silver Electrodes -- 3.2.5.2 Fabrication of Ag/AgCl Reference Electrode -- 3.2.5.3 Optimized Fabrication Procedure -- 3.2.6 Discrimination of Beers
  • 3.2.6.1 Electrode Matrix for the Discrimination of Beer Samples -- 3.2.6.2 Electrode Characterization -- 3.2.6.3 Electronic Tongue -- 3.2.6.4 Beer Samples -- 3.2.6.5 Chemometric Analysis -- Analysis of All Beer Samples (34 Samples) -- Analysis of Pilsner Beers (13 Samples) -- Analysis of Other (Non-Pilsner) Beer Types -- 3.2.7 Minimization of Sample Volume -- 3.2.8 Discrimination of Wines -- 3.2.8.1 Electrode Matrix for the Discrimination of Wine Samples -- 3.2.8.2 Electrode Characterization -- 3.2.8.3 Electronic Tongue -- 3.2.8.4 Wine Samples -- 3.2.8.5 Chemometric Analysis -- 3.2.9 Detection with a Multimeter -- 3.3 Results and Discussion -- 3.3.1 Development of Potentiometric Sensors -- 3.3.1.1 Choice of Electrode Material -- 3.3.1.2 Choice of Insulation -- 3.3.1.3 Type of Paper -- 3.3.1.4 Electrode Architecture -- 3.3.2 Discrimination of Forged Water Samples -- 3.3.2.1 Electrode Characterization -- 3.3.2.2 Chemometric Analysis -- 3.3.3 Integration of Reference Electrode -- 3.3.3.1 Preparation of Silver Electrodes -- 3.3.3.2 Fabrication of Ag/AgCl Reference Electrode -- 3.3.4 Discrimination of Beers -- 3.3.4.1 Electrode Characterization -- 3.3.4.2 Chemometric Analysis -- Analysis of All Beer Samples (34 Samples) -- Analysis of Pilsner Beers (13 Samples) -- Analysis of Other (Non-Pilsner) Beer Types -- 3.3.4.3 Stability of Sensor Matrix -- 3.3.5 Minimization of Sample Volume -- 3.3.6 Discrimination of Wines -- 3.3.6.1 Electrode Characterization -- 3.3.6.2 Chemometric Analysis -- 3.3.7 Detection with Multimeter -- 3.4 Partial Conclusions -- References -- Conclusions
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{'f': 'http://opac.lib.rpi.edu/record=b4392751'}
Extent
1 online resource (200 pages)
Form of item
online
Isbn
9783319286723
Media category
computer
Media MARC source
rdamedia
Media type code
c
Sound
unknown sound
Specific material designation
remote

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