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The Resource Adaptive treatment strategies in practice : planning trials and analyzing data for personalized medicine, edited by Michael Kosorok, Erica Moodie

Adaptive treatment strategies in practice : planning trials and analyzing data for personalized medicine, edited by Michael Kosorok, Erica Moodie

Label
Adaptive treatment strategies in practice : planning trials and analyzing data for personalized medicine
Title
Adaptive treatment strategies in practice
Title remainder
planning trials and analyzing data for personalized medicine
Statement of responsibility
edited by Michael Kosorok, Erica Moodie
Contributor
Editor
Publisher
Subject
Language
eng
Summary
Personalized medicine is a medical paradigm that emphasizes systematic use of individual patient information to optimize that patient's health care, particularly in managing chronic conditions and treating cancer. In the statistical literature, sequential decision making is known as an adaptive treatment strategy (ATS) or a dynamic treatment regime (DTR). The field of DTRs emerges at the interface of statistics, machine learning, and biomedical science to provide a data-driven framework for precision medicine. The authors provide a learning-by-seeing approach to the development of ATSs, aimed at a broad audience of health researchers. All estimation procedures used are described in sufficient heuristic and technical detail so that less quantitative readers can understand the broad principles underlying the approaches. At the same time, more quantitative readers can implement these practices. Adaptive Treatment Strategies in Practice: Planning Trials and Analyzing Data for Personalized Medicine provides the most up-to-date summary of the current state of the statistical research in personalized medicine, contains chapters by leaders in the area from both the statistics and computer sciences fields, contains a range of practical advice, introductory and expository materials, and case studies
Member of
Cataloging source
CaBNVSL
Index
index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Series statement
ASA-SIAM statistics and applied probability series
Target audience
adult
Adaptive treatment strategies in practice : planning trials and analyzing data for personalized medicine, edited by Michael Kosorok, Erica Moodie
Label
Adaptive treatment strategies in practice : planning trials and analyzing data for personalized medicine, edited by Michael Kosorok, Erica Moodie
Link
http://libproxy.rpi.edu/login?url=http://epubs.siam.org/doi/book/10.1137/1.9781611974188
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Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier MARC source
rdacarrier
Color
black and white
Content category
text
Content type MARC source
rdacontent
Contents
Preface -- 1. Introduction -- part I. Design of trials for estimating dynamic treatment regimes -- 2. DTRs and SMARTs : definitions, designs, and applications -- 3. Efficient design for clinically relevant intent-to-treat comparisons -- 4. SMART design, conduct, and analysis in oncology -- 5. Sample size calculations for clustered SMART designs -- part II. Practical challenges in dynamic treatment regime analyses -- 6. Analysis in the single-stage setting : an overview of estimation approaches for dynamic treatment regimes -- 7. G-estimation for dynamic treatment regimes in the longitudinal setting -- 8. Outcome weighted learning methods for optimal dynamic treatment regimes -- 9. Value search estimators for optimal dynamic treatment regimes -- 10. Evaluation of longitudinal dynamics with and without marginal structural working models -- 11. Imputation strategy for SMARTs -- 12. Clinical trials for personalized dose finding -- 13. Methods for analyzing DTRs with censored survival data -- 14. Outcome weighted learning with a reject option -- 15. Estimation of dynamic treatment regimes for complex outcomes : balancing benefits and risks -- 16. Practical reinforcement learning in dynamic treatment regimes -- 17. Reinforcement learning applications in clinical trials
http://library.link/vocab/cover_art
https://contentcafe2.btol.com/ContentCafe/Jacket.aspx?Return=1&Type=S&Value=9781611974188&userID=ebsco-test&password=ebsco-test
Dimensions
unknown
http://library.link/vocab/discovery_link
{'f': 'http://opac.lib.rpi.edu/record=b3782517'}
Extent
1 PDF (xvi, 348 pages).
File format
multiple file formats
Form of item
online
Isbn
9781611974188
Media category
electronic
Media MARC source
isbdmedia
Publisher number
SA21
Reformatting quality
access
Specific material designation
remote
System details
  • Mode of access: World Wide Web
  • System requirements: Adobe Acrobat Reader

Library Locations

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      110 8th St, Troy, NY, 12180, US
      42.729766 -73.682577
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